Q4R3X9

PR
Gene name
FAM220A (SIPAR, QtsA-13353)
Protein name
Protein FAM220A
Names
STAT3-interacting protein as a repressor
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-219 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R3X9

Entry ID Method Resolution Chain Position Source
AF-Q4R3X9-F1 Predicted AlphaFoldDB

No variants for Q4R3X9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R3X9

No associated diseases with Q4R3X9

11 regional properties for Q4R3X9

Type Name Position InterPro Accession
domain RNA polymerase sigma-70 159 - 172 IPR000943-1
domain RNA polymerase sigma-70 183 - 191 IPR000943-2
domain RNA polymerase sigma-70 307 - 319 IPR000943-3
domain RNA polymerase sigma-70 328 - 354 IPR000943-4
domain RNA polymerase sigma factor 70, region 1.1 14 - 84 IPR007127
domain RNA polymerase sigma-70 region 3 214 - 290 IPR007624
domain RNA polymerase sigma-70 region 2 135 - 204 IPR007627
domain RNA polymerase sigma-70 region 4 304 - 356 IPR007630
domain RNA polymerase sigma-70 region 1.2 97 - 128 IPR009042
domain RNA polymerase sigma factor RpoD, C-terminal 131 - 367 IPR012760
domain RNA polymerase sigma-70 like domain 131 - 356 IPR014284

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Cytoplasmic vesicle, secretory vesicle, acrosome
  • Localizes to both nucleus and cytoplasm but located predominantly in the nucleus
  • Detected in the sperm acrosome prior to the acrosome reaction and is likely to be released from acrosome-reacted sperm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRDRRGSLGT CLAQVQQARG GDSNKLSYSL KKRMPMEGLW PADAPSWMNK PVVDGNSQSE
70 80 90 100 110 120
ALSLEMRKDP SGAGPWLHGG GPVLPYVKES VRRNPASAAT RSTAVGLLPA PTECFAQVAC
130 140 150 160 170 180
SGVEALERDW LGGGARATDG HRGQCPKGEP RVSRLLCHQK LPEMGSFQDD PPNALPKGLG
190 200 210 220 230 240
SELEPSCLHS VLSATLHACP EVLLNDETKR VFLDRLKPMF SKQTMEFKKM LKNTSDGLQI
250
TLGLLALQPF ELANSLCHS