Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4R335
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4R335-F1 | Predicted | AlphaFoldDB |
No variants for Q4R335
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4R335 | |||||
No associated diseases with Q4R335
2 regional properties for Q4R335
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SLC41A/MgtE, integral membrane domain | 200 - 333 | IPR006667-1 |
| domain | SLC41A/MgtE, integral membrane domain | 414 - 556 | IPR006667-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| inorganic cation transmembrane transporter activity | Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| metal ion transport | The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTNSKGRSIT | DKTSGGPSNG | GGFVDWTLRL | NTIQSDKFLN | LLLSMVPVIY | QKNQEDRHKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ANGIWQDGLS | TAVQTFSNRS | EQHMEYHSFS | EQSFHANNGH | ASSSCSQKYD | DYANYNYCDG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RETSETTAML | QDEDVSSDGD | EDAIVEVTPK | LPKESSGIMA | LQILVPFLLA | GFGTVSAGMV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LDIVQHWEVF | RKVTEVFILV | PALLGLKGNL | EMTLASRLST | AVNIGKMDSP | IEKWNLIIGN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LALKQVQATV | VGFLAAVAAI | ILGWIPEGKY | YLDHSILLCS | SSVATAFIAS | LLQGIIMVGV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IVGSKKTGIN | PDNVATPIAA | SFGDLITLAI | LAWISQGLYS | CLETYYYISP | LVGVFFLALT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PIWIIIAAKH | PATRTVLHSG | WEPVITAMVI | SSIGGLILDT | TVSDPNLVGI | VVYTPVINGI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GGNLVAIQAS | RISTYLHLHS | IPGELPDEPK | GCYYPFRTFF | GPGVNNKSAQ | VLLLLVIPGH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LIFLYTIHLM | KSGHTSLTII | FIVVYLFAAV | LQVFTLLWIA | DWMVHHFWRK | GKDPDSFSIP |
| 550 | 560 | 570 | |||
| YLTALGDLLG | TALLALSFHF | LWLIGDRDGD | VGD |