Q4R1C4

PR
Gene name
gls93
Protein name
Exo-beta-D-glucosaminidase
Names
Species
Hypocrea jecorina (Trichoderma reesei)
KEGG Pathway
ag:BAD99604
EC number
3.2.1.165: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4R1C4

Entry ID Method Resolution Chain Position Source
AF-Q4R1C4-F1 Predicted AlphaFoldDB

No variants for Q4R1C4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4R1C4

No associated diseases with Q4R1C4

3 regional properties for Q4R1C4

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich 227 - 326 IPR006102
domain Exo-beta-D-glucosaminidase, Ig-fold domain 778 - 885 IPR041351
domain Mannosidase Ig/CBM-like domain 684 - 766 IPR041447

Functions

Description
EC Number 3.2.1.165 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Secreted, extracellular space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

2 GO annotations of molecular function

Name Definition
exo-1,4-beta-D-glucosaminidase activity Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.
hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of any O-glycosyl bond.

2 GO annotations of biological process

Name Definition
chitin catabolic process The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLANAIAALL LGSGIASAAG HGSPLTSKAG HRAVIPDWDL KSSSDVSKDL GGLSKPGVDT
70 80 90 100 110 120
SSWYHAGTSR CTIMGCLINA GVYNDEELWY SDNLNHVNWG QFSVPWVYRH EFALSPAKGK
130 140 150 160 170 180
HFLLQTNGIT SKADLFFNGK QIADKEYQSG AYAGRTYDIT NLAAKKNALL VQVYPTDYLY
190 200 210 220 230 240
DFALGYVDWN PYPSDNGSGI WRDITIKETG SVSMGPVSVL VDIDVPVEKN PARVTVRAEA
250 260 270 280 290 300
QNLESHAVEF NAAAVISGNS CSGEALKQTI KLAPGEKKLV QFTQTIKTPS IWWPKQWGDQ
310 320 330 340 350 360
PLYTAEVTFS VKGAVSDTAQ TKFGVRKVTS FVNQFNDTQY SVNGHPFQVI GGGYGADMFL
370 380 390 400 410 420
RWDSERFTRI VEYMLDMHQN TIRLEGKMEH PELYEICDEY GLMVMPGWEC CDKWEAWAYN
430 440 450 460 470 480
DELAIFPPPV WDANDYETAN YSMIHEAAMM QPHPSVLTFL VGSDFWPNDE AVVLYANALK
490 500 510 520 530 540
NAGWQTPIIA SASKRGFPAL LGPGGMKMDG PYDWVPPNYW YDVEPSEDRL GAAFGFGSEL
550 560 570 580 590 600
GAGVGTPELS SLRRFLNQSD LDDLWKNPNK NLFHMSTNAS SFYNRKIYNQ GLWKRYGAPT
610 620 630 640 650 660
SLDDYLLKAQ MMDYEATRAQ YEGFGALWTA SRPATGVIYW MLNNAWPSLH WNQFDYYLHP
670 680 690 700 710 720
AGSYFGTKVG SRIEHVAYNY QKKEIWVINH SLYQTGSRNI KVELIDMNGK QIAKKLVQVR
730 740 750 760 770 780
TKANSGFKAM DISSDINKLS SVAFLRLVLS DEKGSVLSRN VYWVTKTIDE LNWDESTWYY
790 800 810 820 830 840
TPVSKFVDYT PLNTLATAQV SVTTSGGKHL PGIPGSQTRT VTLENKSSVP AVFIRLTLVD
850 860 870 880 890
SKGNDVNPVS WSDNYVTLWP HEKLQLEVGG WDGSGDKIQI SGKNIKATTV KL