Q4QL71

PR
Gene name
ppc
Protein name
Phosphoenolpyruvate carboxylase
Names
PEPC, PEPCase
Species
Haemophilus influenzae (strain 86-028NP)
KEGG Pathway
hit:NTHI1403
EC number
4.1.1.31: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-196 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4QL71

Entry ID Method Resolution Chain Position Source
AF-Q4QL71-F1 Predicted AlphaFoldDB

No variants for Q4QL71

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4QL71

No associated diseases with Q4QL71

2 regional properties for Q4QL71

Type Name Position InterPro Accession
active_site Phosphoenolpyruvate carboxylase, Lys active site 134 - 145 IPR018129
active_site Phosphoenolpyruvate carboxylase, His active site 536 - 548 IPR033129

Functions

Description
EC Number 4.1.1.31 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoenolpyruvate carboxylase activity Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.

3 GO annotations of biological process

Name Definition
carbon fixation A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
oxaloacetate metabolic process The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQEYSTLRN NISMLGRFLG ETINDAQGED ILELIENIRK LSRNSRAGDD KARQALLDTL
70 80 90 100 110 120
GSISNENIIP VARAFSQFLN LTNIAEQYQT ISREHSLAQS SSQSLSELFK RLKEQNASVE
130 140 150 160 170 180
EVHKTVEKLL IELVLTAHPT ETTRRSLIHK HIEINKCLSK LEHHDLTEKE RNIIERLLLR
190 200 210 220 230 240
LIAEAWHTNE IRTVRPTPFD EAKWGFAMLE NSLWQAVPEF LRQLNETARE FLGYDLPVGL
250 260 270 280 290 300
KPVRISSWMG GDRDGNPFVT AQITKKVLYF ARWKAADLFL QDISKLADEL SMMKCSDEFR
310 320 330 340 350 360
DKYGEHLEPY RFVVKNLRNQ LTATLAYFDD HLSNRTPRVS ESEIILEDNQ LWEPLYDCYQ
370 380 390 400 410 420
SLIQCGMRII ANGSLLDILH RISCFGVTLS QMDIRQESTR HTDAIAEIMR YIGLGDYSQW
430 440 450 460 470 480
MEDDKQAFLI RELSSRRPLI PQNWTPSPET KEILDTCKVI AQQKQGVIAC YVISMARSAS
490 500 510 520 530 540
DVLAVHLLLK EAGVPYHIPV VPLFETLEDL DAAEKVMTQL FNVGWYRGVI NNRQMVMIGY
550 560 570 580 590 600
SDSAKDAGMM AASWAQYRAQ EALVNLTEKL GIELTLFHGR GGTIGRGGAP AHAALLSQPP
610 620 630 640 650 660
RSLKNGLRVT EQGEMIRFKL GLPAVAVETF DLYASAILEA NLLPPPEPKP EWRTIMDELS
670 680 690 700 710 720
TISCDIYRGV VRGDKDFVPY FRSATPEQEL SKLPLGSRPA KRNPNGGVES LRAIPWIFAW
730 740 750 760 770 780
MQNRLMLPAW LGAGAAIRQV IEQGKGDIIH KMCENWPFFS TRIGMLEMVF SKSDTWLSQQ
790 800 810 820 830 840
YDQRLVKKEL WYLGENLRKQ LEDDIQTVLS LSHQSELMSD LPWIADSIAL RNIYTDPLNL
850 860 870
LQVELLHRFR ENPEQVNPDV EQALMITITG IAAGMRNTG