Q4QK37

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Haemophilus influenzae (strain 86-028NP)
KEGG Pathway
hit:NTHI1844
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-288 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4QK37

Entry ID Method Resolution Chain Position Source
AF-Q4QK37-F1 Predicted AlphaFoldDB

No variants for Q4QK37

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4QK37

No associated diseases with Q4QK37

6 regional properties for Q4QK37

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 343 - 513 IPR000795
domain Small GTP-binding protein domain 346 - 503 IPR005225
domain Translation initiation factor IF-2, N-terminal 268 - 318 IPR006847
domain Initiation factor 2 associated domain, bacterial 10 - 45 IPR013575
domain Translation initiation factor IF- 2, domain 3 620 - 734 IPR023115
domain Translation initiation factor IF-2, domain II 520 - 613 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEDVKADAP KKLSIQRRTK TTVSSTTTGG KSKEVQVEVR KKRTVKTDIA QQEEAKLKAQ
70 80 90 100 110 120
QEAEAKKIAE QKAAEEKARL EAEKAATKKE ADEKSKAEKA KAETAKPAKS AVDSKAKFVD
130 140 150 160 170 180
PEKEKRKAEE AELRRKAEEV ARQKAEEQAR RAAEEAKRYA EADDSDNESS SEDYSDYNLS
190 200 210 220 230 240
SRYALEAEDE EDRRNENRGR GKNKVAKAKK GGRDDENSKN SKNERESNRK NQKDAKFGKG
250 260 270 280 290 300
KNGKKGTALQ QAFTKPVQVV KADVVIGETI TVAELANKMS VKATEIIKVM MKMGEMVTIN
310 320 330 340 350 360
QVIDQETAQL VAEELGHKVI LRNENELEEA VLGDRDVNAE KVTRAPVVTI MGHVDHGKTS
370 380 390 400 410 420
LLDYIRKAKV AAGEAGGITQ HIGAYHVEMD DGKMITFLDT PGHAAFTSMR ARGAKATDIV
430 440 450 460 470 480
VLVVAADDGV MPQTIEAIQH AKAAGAPLVV AVNKIDKPEA NPDRVEQELL QHDVISEKFG
490 500 510 520 530 540
GDVQFVPVSA KKGTGVDDLL DAILLQSEVL ELTAVKDGMA SGVVIESYLD KGRGPVATIL
550 560 570 580 590 600
VQSGTLRKGD IVLCGFEYGR ARAMRDENGK EVDEAGPSIP VELLGLSGVP AAGDEATVVR
610 620 630 640 650 660
DEKKAREVAL YRQGKFREVK LARQQKAKLE NMFSNMSEGD VAELNVIVKA DVQGSVEAIV
670 680 690 700 710 720
QALNELSTNE VKVKVVGSGV GGITETDATL ATASNAIIVG FNVRADATAR RVIEAENIDL
730 740 750 760 770 780
RYYSIIYELL NEIKAAMSGM LEPEFKQEII GLAEVRDVFR HPKFGAIAGC MVTEGVVKRN
790 800 810 820 830 840
NPIRVLRDNV VIFEGELESL RRFKDDVSEV RNGMECGIGV KNYNDVKVGD QIEVFEVVEV
KRSI