Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4PHC3

Entry ID Method Resolution Chain Position Source
AF-Q4PHC3-F1 Predicted AlphaFoldDB

No variants for Q4PHC3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4PHC3

No associated diseases with Q4PHC3

3 regional properties for Q4PHC3

Type Name Position InterPro Accession
domain Phox homology 302 - 418 IPR001683
domain SNX8/Mvp1, PX domain 304 - 415 IPR035704
domain Sorting nexin 8/Mvp1, BAR domain 442 - 674 IPR045734

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome A vacuole to which materials ingested by endocytosis are delivered.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol-3-phosphate binding Binding to phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.

2 GO annotations of biological process

Name Definition
protein targeting to vacuole The process of directing proteins towards the vacuole, usually using signals contained within the protein.
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRHHRPFTW GGAQPGASFS NPTSPTLEAS TFGFEPSVPD IYRRAWILVT KDASAELFAD
70 80 90 100 110 120
TSDADIHLGL LHKLLTSAGG LGPGSAEQIV NSACKGSRCS RSDFYCALGL LHQMQQGEEL
130 140 150 160 170 180
DVHLVQQRLT MGSLSAPVLD LSDATLNPHS HHTFPPTAPS GPSRIDPRPS TFMREMSDPW
190 200 210 220 230 240
NANSSGSYNG IDTRPAYNQY DAMPQQYDTL NSHDSALPAG FAGNVSSGSF ERIKFNAGDD
250 260 270 280 290 300
RRSHQLLAHN QGSSTDTFLA PDRTEARARQ PNTRQERPFS YMSDTAETNA VDAAEDPAAD
310 320 330 340 350 360
LPEDQVTVRL RSELEGFIIK HNVYIVSSSL RKSQVTRRYS DWLWLAECLV KRYPFRCLPV
370 380 390 400 410 420
LPPKRIAMPI AGRHLSADDL FIERRRRGLE RFLRMLTCHP MLREDKLVEV FFTEPRPIAE
430 440 450 460 470 480
WKSSAPALFL DEEGLIKTVD EAERMSIPED LQLKLTQQRQ AIPELLERWT AMVALFERIV
490 500 510 520 530 540
KRNDAAAADY SRLNFSLLSV IETSARRWRP GSDNGKKTEE IMSTMASIFQ DHSDTTSSRV
550 560 570 580 590 600
SAVSLSTLEG MKAQRDLILS FRDLIGRIDR QLVDPIDMLK KRIEASQKRI TTLAASANSN
610 620 630 640 650 660
SASIQQEQAT LSAQVKQDTQ SIQKYLNRRI HAKKTVWEEL IWFHHRFKAV EEDMQKFVRD
670 680
ETFFLSTLTR MWEATEMKMK MIR