Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4PGT8

Entry ID Method Resolution Chain Position Source
AF-Q4PGT8-F1 Predicted AlphaFoldDB

No variants for Q4PGT8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4PGT8

No associated diseases with Q4PGT8

5 regional properties for Q4PGT8

Type Name Position InterPro Accession
repeat WD40 repeat 176 - 217 IPR001680-1
repeat WD40 repeat 245 - 286 IPR001680-2
repeat WD40 repeat 352 - 392 IPR001680-3
repeat WD40 repeat 420 - 470 IPR001680-4
repeat WD40 repeat 600 - 634 IPR001680-5

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
regulation of DNA damage checkpoint Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIESNDYEQE RLKNIRENER LMKELGVMGG SSTIGGPSSK RTTPTKPKKQ ATPKKKPDTT
70 80 90 100 110 120
PTRIMPSRSS ARLAGHEADS ETLKRKYEEE AEEARKVAEA AKRARHQPFD LSGMTGGELE
130 140 150 160 170 180
EEAIMALEST LQGLANNTSS AAELVDTKDE NKRRSANKPD PQFSTERREL EDILNKMTLK
190 200 210 220 230 240
SAAKVTPKRI YSMAYHPSTD KDLVFVGDKE GSIGVWDAAP VAFASNRNGV KTADDQDEDA
250 260 270 280 290 300
EERFPEGKAW TLQVHARSPV TCIKFDPVNH NSVLSSSYDS TVRKLDLATA KSEEIWAGEE
310 320 330 340 350 360
DVLLSIFDVL SPSTHPSVYM DTPNPSLDER SMWIADHRGG LLHIDLRERT RRGNNTRRWQ
370 380 390 400 410 420
VCEKKIGAMS VNRLAPHCIA TASLDQHIRL FDVRALASVV KQTADAPYNY KGVDADDLES
430 440 450 460 470 480
AQTKAQFASS KARQACTSVD FSPRGDQLVG VSYDDVVKVW SMEPGSLFSE HGLKNRIATA
490 500 510 520 530 540
KSNKPKGAVK KQVPDSASDT GPGLLSWLSR ATPLGTKKDV AEAIKQEQDA PSPSLSKRPD
550 560 570 580 590 600
DVLANPTRIP HNNQTGKWLT LFRAKWNQNA LLEPHFTIGS MSRRAEVYAA DGTLLRSLWD
610 620 630
ENLVTAVPAV TCMHPVLPAR LVTGNASGRC TFWSPDP