Q4P6I8
Gene name |
MSH3 (UMAG_04275) |
Protein name |
DNA mismatch repair protein MSH3 |
Names |
MutS protein homolog 3 |
Species |
Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus) |
KEGG Pathway |
uma:UMAG_04275 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4P6I8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4P6I8-F1 | Predicted | AlphaFoldDB |
No variants for Q4P6I8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4P6I8 | |||||
No associated diseases with Q4P6I8
5 regional properties for Q4P6I8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA mismatch repair protein MutS, C-terminal | 922 - 1115 | IPR000432 |
| domain | DNA mismatch repair protein MutS-like, N-terminal | 235 - 347 | IPR007695 |
| domain | DNA mismatch repair protein MutS, core | 567 - 904 | IPR007696 |
| domain | DNA mismatch repair protein MutS, connector domain | 368 - 484 | IPR007860 |
| domain | DNA mismatch repair protein MutS, clamp | 738 - 817 | IPR007861 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent DNA damage sensor activity | A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis. |
| double-stranded DNA binding | Binding to double-stranded DNA. |
| mismatched DNA binding | Binding to a double-stranded DNA region containing one or more mismatches. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mismatch repair | A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. |
| mitochondrial DNA repair | The process of restoring mitochondrial DNA after damage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPPPPSQKPG | QASISAFFKP | KSSQRPITKS | CQPDRAQVSN | GYARTSNLLD | TDTGASSSAQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PPHKRSKLNN | KDGPRRETID | RMSKWKFTAL | QPSDNVSSEL | DEAASQATPT | ERSQHDQARH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DAFRKTLLGP | NFAIDRHASN | QMQIDDMSSA | HTFSHSESRT | STGTKVDAMV | VDDDDDDDDN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QHEQAAQSVP | GTWNRFTGLA | APESTPAPCS | HRDSSMNKTK | GKPKASGAGT | GPSYTPLEKQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ILELKAEHPG | VLLIIEVGYK | LKFYGEDARI | ASKELSIMCF | PERNLLTAMI | PVHRLHIHVK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RLIQAGHKVG | VVRQIETRAL | KAASKNAYTP | FVRKLTALYT | ASTWVDDLSS | LDDLAANMGD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AYTNQPKSLM | AIVEQSERGN | AQADRVSIGI | VSVEVNTGHL | TYDQFSDGHA | RSELETRIAH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LAPAEVLIPP | QLTKPTEKVI | SYLLGNGADG | GVRIERLAAM | PDYNQAFQSV | TRFYRDRGLE |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SPEVPEVPEV | PGSSEADTTR | LATTLADGAD | KRSSPLISLI | VSLPQLSLIA | LAQIIQHLQA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FQLESICTLS | TNFRSFSSRT | TMLLNSNTLA | NLEIFRTANE | QTERGSLIWL | LDKCKSAMGR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RLLRKWVSRP | LTDIDKLQER | LDAVEALRDG | KSYVLRRLDS | VLHGLPDLER | GLARMTYGRA |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TPTELATVLL | SLNRVTQEFK | ADEAATWKTQ | SSLIDTHLLS | LASGKQVVQT | YLNQISIKEA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| RANNKADLYL | DADVFPAIQA | SKDNMAIIDG | ELREHLREIR | KLLHRPSLDY | VSVAGVDYLV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| EVRVADAKKV | PVEWLRVSAT | KSMVRFHTPE | VMRLSKIRDQ | HKETLDAAAQ | EAFARFVREL |
| 850 | 860 | 870 | 880 | 890 | 900 |
| CKSEYVVLRN | VVASLAVLDV | LLSLAHVARA | AGYTRPVFLR | QPQDAEASVP | VEIIGMRHAI |
| 910 | 920 | 930 | 940 | 950 | 960 |
| LEVVSAMPYI | PNDVSLSTGD | SGAAILLSGC | NMGGKSSVVR | ALGLVIIMAQ | IGSFVAADVA |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| RIGVHDAVYV | RMGARDRMFS | GRSTYMVEVS | ETADILGSLT | SRSMVILDEL | GRGTSSRDGY |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| CLAAGVLEYL | LTLGCPPNTV | FITHYLQLAS | MQRRYPHLRN | MHMAFTSNSR | NLLDPIHLVY |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| KLRPGIAHSF | GIHAAHLARL | PLQIIHSAST | ISSALYAKHT | NRSAFLVLKH | AFANPPQLAT |
| 1150 | |||||
| VSTLQHLLFT | HPPT |