Q4L8J3
Gene name |
hutG |
Protein name |
Formimidoylglutamase |
Names |
Formiminoglutamase, Formiminoglutamate hydrolase |
Species |
Staphylococcus haemolyticus (strain JCSC1435) |
KEGG Pathway |
sha:SH0723 |
EC number |
3.5.3.8: In linear amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4L8J3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4L8J3-F1 | Predicted | AlphaFoldDB |
No variants for Q4L8J3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4L8J3 | |||||
No associated diseases with Q4L8J3
No regional properties for Q4L8J3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q4L8J3 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.3.8 | In linear amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| formimidoylglutamase activity | Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide. |
| manganese ion binding | Binding to a manganese ion (Mn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine catabolic process to glutamate and formamide | The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide. |
| histidine catabolic process to glutamate and formate | The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYTQGNPKLW | TGRLDSETDP | KQFRHFQTVK | FANLENMENV | SDKTGVGLLG | YAVDKGVENN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KGRIGSRKGP | DIIKHEFAKL | PDLSECEMLI | DYGNVEHTSN | HLRETQQEMA | RLSAKVIKQH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KQAFLIGGGH | DIAYAQYLAT | REVYSDASIG | IINIDAHFDT | RPDEPPTSGT | MFREILDNDE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NVDYLVLGLA | QGGNTRALYD | YAKDNNIIYV | YADELLHQVS | PTIKDKIERF | IHDHDTIMFT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ICMDVIDSAF | APGVSSPSVL | GLYPHSVFEI | SKRVILSDKV | SSISIAETNP | DYDVDNRTSK |
| 310 | |||||
| LAANLIHHFL | V |