Q4L868

PR
Gene name
lacG
Protein name
6-phospho-beta-galactosidase
Names
Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG
Species
Staphylococcus haemolyticus (strain JCSC1435)
KEGG Pathway
sha:SH0848
EC number
3.2.1.85: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4L868

Entry ID Method Resolution Chain Position Source
AF-Q4L868-F1 Predicted AlphaFoldDB

No variants for Q4L868

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4L868

No associated diseases with Q4L868

2 regional properties for Q4L868

Type Name Position InterPro Accession
active_site Glycoside hydrolase family 1, active site 370 - 378 IPR018120
conserved_site Glycosyl hydrolases family 1, N-terminal conserved site 8 - 22 IPR033132

Functions

Description
EC Number 3.2.1.85 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
6-phospho-beta-galactosidase activity Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.

1 GO annotations of biological process

Name Definition
lactose catabolic process via tagatose-6-phosphate The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLPEDFIF GGATAAYQAE GATQTDGKGR VAWDTYLEEN YWYTAEPASD FYNKYPIDLE
70 80 90 100 110 120
LSEKFGVNGI RISIAWSRIF PKGYGEVNPK GVEYYHNLFK ECHRRHVEPF VTLHHFDTPE
130 140 150 160 170 180
TLHSDGDFLN RKTIEYFVEY AKFCFEEFEE VNYWTTFNEI GPIGDGQYLV GKFPPGIKYD
190 200 210 220 230 240
FAKVFQSHHN MMVAHAKAVK LFKDNGYSGE VGVVHALPTK YPYDPTNPED VRAAELEDII
250 260 270 280 290 300
HNKFILDATY LGKYSRETME GVQHILSVNG GKLDIPEEDY KVLEAAKDLN DFLGINYYMS
310 320 330 340 350 360
DWMRGYDGES EITHNATGDK GGSKYQLKGV GQREFDVDVP RTDWDWMIYP KGLYDQIMRV
370 380 390 400 410 420
VKDYPNYHKI YITENGLGYK DQFDEERKTV DDDARIDYVK KHLEVISDAI RDGANVKGYF
430 440 450 460
IWSLMDVFSW SNGYEKRYGL FYVDFETQER YPKKSAYWYK ELAESKEIK