Q4L742

PR
Gene name
accD
Protein name
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Names
ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta
Species
Staphylococcus haemolyticus (strain JCSC1435)
KEGG Pathway
sha:SH1224
EC number
2.1.3.15: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4L742

Entry ID Method Resolution Chain Position Source
AF-Q4L742-F1 Predicted AlphaFoldDB

No variants for Q4L742

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4L742

No associated diseases with Q4L742

3 regional properties for Q4L742

Type Name Position InterPro Accession
domain Acetyl-coenzyme A carboxyltransferase, N-terminal 30 - 288 IPR011762
domain Acetyl-CoA carboxylase 64 - 243 IPR034733
domain Acetyl-coA carboxylase zinc finger domain 32 - 56 IPR041010

Functions

Description
EC Number 2.1.3.15 Carboxy- and carbamoyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
acetyl-CoA carboxylase complex A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.

4 GO annotations of molecular function

Name Definition
acetyl-CoA carboxylase activity Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
carboxyl- or carbamoyltransferase activity Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
malonyl-CoA biosynthetic process The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKDFFNRSS KKRKYLTVQD SKQNEVPAGI MTKCPKCKKI MYTKELNENL NVCFNCDHHI
70 80 90 100 110 120
ALPAYKRIEA ITDENSFVEF DKGMTSANPL DFPGYQEKIE KDQQKTDLSE AVVTGTAKLD
130 140 150 160 170 180
GVQFGVAVMD ARFRMGSMGS VVGEKICRII DYATEHRLPF ILFSASGGAR MQEGIISLMQ
190 200 210 220 230 240
MGKTSVSLKR HSDAGLLYIS YLTHPTTGGV SASFASVGDI NLSEPKALIG FAGRRVIEQT
250 260 270 280
INEKLPDDFQ TAEFLLEHGQ LDKVVHRKEM KETLAQLLKL HQEVKKDA