Q4L6K3

PR
Gene name
proC
Protein name
Pyrroline-5-carboxylate reductase
Names
P5C reductase, P5CR, PCA reductase
Species
Staphylococcus haemolyticus (strain JCSC1435)
KEGG Pathway
sha:SH1413
EC number
1.5.1.2: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

185-262 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4L6K3

Entry ID Method Resolution Chain Position Source
AF-Q4L6K3-F1 Predicted AlphaFoldDB

No variants for Q4L6K3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4L6K3

No associated diseases with Q4L6K3

2 regional properties for Q4L6K3

Type Name Position InterPro Accession
domain Pyrroline-5-carboxylate reductase, catalytic, N-terminal 3 - 98 IPR028939
domain Pyrroline-5-carboxylate reductase, dimerisation domain 161 - 265 IPR029036

Functions

Description
EC Number 1.5.1.2 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
pyrroline-5-carboxylate reductase activity Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.

1 GO annotations of biological process

Name Definition
L-proline biosynthetic process The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKLVFYGAGN MAQAIFKGII NSKKLKSHDI YLTNKSNEEA LKNFAEELGV EYSYDDEKLL
70 80 90 100 110 120
QDADYVFLGS KPYDFEKVAQ RIQPYINENN RFISIMAGLP INYIQEQLQV ENPIARIMPN
130 140 150 160 170 180
TNAQVGHSVT GISFSGNFGP KSKEEVNDLV NAFGSVIEVD EDHLHQVTAI TGSGPAFLYH
190 200 210 220 230 240
VFEQYVKAGT DLGLEKDQVE ESIKNLIIGT SKMIERSDLS MEQLRKNITS KGGTTQAGLN
250 260 270
ALAQHDIEAI FKDCLNAAVH RSVELSKNED N