Q4L4G8

PR
Gene name
pepT
Protein name
Peptidase T
Names
Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase
Species
Staphylococcus haemolyticus (strain JCSC1435)
KEGG Pathway
sha:SH2148
EC number
3.4.11.4: Aminopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4L4G8

Entry ID Method Resolution Chain Position Source
AF-Q4L4G8-F1 Predicted AlphaFoldDB

No variants for Q4L4G8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4L4G8

No associated diseases with Q4L4G8

3 regional properties for Q4L4G8

Type Name Position InterPro Accession
domain Xaa-Pro dipeptidyl-peptidase-like domain 200 - 523 IPR000383
domain Xaa-Pro dipeptidyl-peptidase, C-terminal 537 - 792 IPR013736
domain X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain 1 - 155 IPR015251

Functions

Description
EC Number 3.4.11.4 Aminopeptidases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
metallopeptidase activity Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
tripeptide aminopeptidase activity Catalysis of the hydrolysis of a single N-terminal amino acid residue from a tripeptide.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
peptide catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKAQLIDRLS RYVKIDTQSN PESSTTPSTE KQWDLLRLLQ QELEGFGLET NLDDNGYLFA
70 80 90 100 110 120
TLESNVSFDV PTVGFLAHVD TSPDFNASNV NPQIVEQYDG KTIKLGDTGR VLSQETFPEL
130 140 150 160 170 180
KKLIGHTLMI TDGTSLLGAD DKAGVVEIME AVKYLIEHPE IKHGRIRIAF TPDEEIGRGP
190 200 210 220 230 240
HKFDVERFNA DFAYTMDGSE FGELQFESFN AAEANITTHG VNVHPGSAKN IMVNAISLGH
250 260 270 280 290 300
QFHSLLPAGE VPERTEDYEG FYHLMKFEGN VEKATLQYII RDHDRESFEL RKKKLLEIRD
310 320 330 340 350 360
DINVHYEDFP VKVDIEDQYY NMAEKIEPHP YIIDIPKKVF NDLNIEPNTA PIRGGTDGSQ
370 380 390 400
LSFKGLPTPN IFTGCGNFHG PFEYASIDVM EKAVQVIIGI AQEVTHHHK