Q4KHH8

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
KEGG Pathway
pfl:PFL_1174
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

162-234 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4KHH8

Entry ID Method Resolution Chain Position Source
AF-Q4KHH8-F1 Predicted AlphaFoldDB

No variants for Q4KHH8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4KHH8

No associated diseases with Q4KHH8

6 regional properties for Q4KHH8

Type Name Position InterPro Accession
domain ACT domain 706 - 789 IPR002912-1
domain ACT domain 815 - 895 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 66 - 114 IPR002934
domain HD/PDEase domain 457 - 611 IPR003607
domain HD domain 461 - 583 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 185 - 322 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPQVDPELFD RGQFQAELAL KASPIAAFKK AIRQAREVLD TRFRSGREIR RLIEDRAWFI
70 80 90 100 110 120
DNILQKAWDQ FSWSEDADIA LVAVGGYGRG ELHPYSDIDL LILLDSADHE IFRDSIERFL
130 140 150 160 170 180
TLLWDIGLEV GQSVRSVDEC AEQARADLTV ITNLMESRTI AGPEHLRQRM LQVTSTEHMW
190 200 210 220 230 240
PSKDFFLAKR AEQKARHHKY NDTEYNLEPN VKGSPGGLRD IQTILWVARR QYGTLNLRAL
250 260 270 280 290 300
AGEGFLVESE NALLASSQEF LWKVRYALHM LAGRAEDRLL LDHQRSIATL LGFEGEDAKQ
310 320 330 340 350 360
SIESFMQQYY RVVMSIAQLS DLIIQHFEEV ILAPEDEAPP QPINARFQLH DGYIEAINDN
370 380 390 400 410 420
VFKRTPFAML EIFVLMAQHP EIKGVRADTI RLLREHRHLI DDDFRHDIRN TSLFIELFKC
430 440 450 460 470 480
EIGIHRNLRR MNRYGILGRY LPEFGFIVGQ MQHDLFHIYT VDAHTLNLIK HLRKMQYTPI
490 500 510 520 530 540
SEKFPLASKL MGKLPKPELI YLAGLYHDIG KGRHGDHSEI GAVDAEAFCV RHQLPQWDTR
550 560 570 580 590 600
LIVWLVQNHL VMSTTAQRKD LSDPQVIHDF AQIVVDQTRL DYLYVLTVAD IYATNPTLWN
610 620 630 640 650 660
SWRASLLRQL YTETKRALRR GLENPVDREE QIRQTQSAAL DILVRNGTDP DEVEQLWSQL
670 680 690 700 710 720
GDDYFLRHTA GDVAWHSDAI LQQPADGGPL VLIKEITQRE FEGGTQIFIY APDQHDFFAV
730 740 750 760 770 780
TVAAMDQLNL NIHDARIITS SSQFTLDTYI VLDNDGESIG NNPQRVEQIR KGLTDALRNP
790 800 810 820 830 840
DDYPTIIQRR VPRQLKHFAF APEVTIHNDA QRPVTVLELS APDRPGLLAR IGKIFLEFDL
850 860 870 880 890
SLQNAKIATL GERVEDVFFI TDAHNQPLSD PQLCSRLQDA IVEQLSVSHE PTIEMTRLSI