Q4KHE9
Gene name |
truD |
Protein name |
tRNA pseudouridine synthase D |
Names |
tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D |
Species |
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) |
KEGG Pathway |
pfl:PFL_1203 |
EC number |
5.4.99.27: Transferring other groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4KHE9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4KHE9-F1 | Predicted | AlphaFoldDB |
No variants for Q4KHE9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4KHE9 | |||||
No associated diseases with Q4KHE9
1 regional properties for Q4KHE9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Gcp-like domain | 2 - 333 | IPR000905 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.99.27 | Transferring other groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| tRNA pseudouridine synthase activity | Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA pseudouridine synthesis | The intramolecular conversion of uridine to pseudouridine in a tRNA molecule. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNELQLLGPR | AYGDALGSAV | LKATAEDFQV | DEVLDIPLSG | EGEHLWLWVE | KRGLNTEEAA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RRIAKAAGVS | LRTVSYAGLK | DRQALTRQWF | SVQLPGKADP | DLGAAENHTL | KILEATRHKR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KLQRGAHAAN | GFTLRLTELK | ADQAAIDERL | KRIAAQGIPN | YFGAQRFGHD | GGNLVDARSW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AARQALPEQR | NVRSRLLSTA | RSYLFNQALA | ARVADGTWQQ | AQVGDLLAFT | DSRSFFMAGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DECTDPRLAI | LDLHPTGPLW | GEGESPAGGA | VHELEQQMAD | REAALCEWLI | KAGMSHERRI |
| 310 | 320 | 330 | 340 | 350 | |
| LRLPIGGLTW | HYPEPDILQL | EFVLPAGCFA | TALVRELVDL | VPVGQTDSSC | AF |