Q4K9A4

PR
Gene name
macB2
Protein name
Macrolide export ATP-binding/permease protein MacB 2
Names
Species
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
KEGG Pathway
pfl:PFL_4082
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

105-174 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4K9A4

Entry ID Method Resolution Chain Position Source
AF-Q4K9A4-F1 Predicted AlphaFoldDB

No variants for Q4K9A4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4K9A4

No associated diseases with Q4K9A4

15 regional properties for Q4K9A4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 391 - 608 IPR000795
domain Hint domain C-terminal 367 - 412 IPR003586
domain Hint domain N-terminal 18 - 130 IPR003587
domain Intein DOD homing endonuclease 171 - 215 IPR004042
domain Translation elongation factor EFTu-like, domain 2 634 - 712 IPR004161
domain Homing endonuclease, LAGLIDADG 179 - 240 IPR004860
domain Small GTP-binding protein domain 407 - 535 IPR005225
ptm Intein N-terminal splicing region 20 - 110 IPR006141
domain Intein 97 - 110 IPR006142-1
domain Intein 181 - 193 IPR006142-2
domain Intein 202 - 217 IPR006142-3
domain Intein 384 - 401 IPR006142-4
domain Translation initiation factor IF- 2, domain 3 722 - 833 IPR023115
domain Elongation factor Tu-type domain 854 - 940 IPR029459
domain Intein C-terminal splicing region 386 - 407 IPR030934

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQTPLIDLRN IRKSYGGGDS PQVDVLRGID LSIHAGEFVA IVGASGSGKS TLMNILGCLD
70 80 90 100 110 120
RPTSGEYLFA GENVAHLDSD ELAWLRREAF GFVFQGYHLI PSASAQENVE MPAIYAGTPT
130 140 150 160 170 180
AERHTRAAAL LERLGLASRS GNRPHQLSGG QQQRVSIARA LMNGGHIILA DEPTGALDSH
190 200 210 220 230 240
SGAEVMALLD ELASQGHVVI LITHDREVAA RAKRIIEIRD GEIISDTATS DPSVQLSANA
250 260 270 280 290 300
GALQAVDLRQ RLADGSEPTG AWKGELLEAI QAAWRVMWIN RFRTALTLLG IIIGVASVVV
310 320 330 340 350 360
MLAVGEGSKR QVMAQMGAFG SNIIYLSGYS PNPRTPEGIV TLDDVAALAN LPQVKRIMAV
370 380 390 400 410 420
NGAKAGVRFG NADYMSYVGG NDTNFPEIFN WPVAQGSYFS EADESSAAAV AVIGHKVREK
430 440 450 460 470 480
LLKDVANPIG QYILIENVPF QVVGVLSEKG ASSGDSDSDD RIAVPYSAAS IRLFGDHNPQ
490 500 510 520 530 540
YVAIAAADAS RVKQTEQEID ELMLRMHGGK RDFELTNNAA MIQAEARTQN TLSLMLGAIA
550 560 570 580 590 600
AISLLVGGIG VMNIMLMTVR ERTREIGIRM ATGARQRDIL RQFLTEAVML SVVGGLAGIG
610 620 630 640 650
VALIIGGILI LSEVAVAFSL AAVLGAFACA LVTGVIFGFM PARKAARLDP VTALTSE