Q4J8F1

PR
Gene name
argG
Protein name
Argininosuccinate synthase
Names
Citrulline--aspartate ligase
Species
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
KEGG Pathway
sai:Saci_1617
EC number
6.3.4.5: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

132-230 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4J8F1

Entry ID Method Resolution Chain Position Source
AF-Q4J8F1-F1 Predicted AlphaFoldDB

No variants for Q4J8F1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4J8F1

No associated diseases with Q4J8F1

3 regional properties for Q4J8F1

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 274 - 283 IPR020557
domain Fumarate lyase, N-terminal 6 - 299 IPR022761
domain Argininosuccinate lyase, C-terminal 362 - 429 IPR029419

Functions

Description
EC Number 6.3.4.5 Other carbon--nitrogen ligases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
argininosuccinate synthase activity Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKIVLAYSGG LDTTVAIRWL RETFNADVTT VTVDVGQKDD FYQIEKRAYI AGAIKHYTID
70 80 90 100 110 120
AKKDFAERYI SYAIKMNGLY EDIYPLSTAL ARPLIVEKVV EIAKKIGAEA IAHGSTSKGN
130 140 150 160 170 180
DQVRFDLAVK ALYPEAKIIA PARIWNMTRD KEIEYAKSKG IPIKTESSKY SIDENLWGRS
190 200 210 220 230 240
IEGDIISDPS KEVPEDAFEW TKKTKDDKLK ISLTFDKGLP VEVNGEKMDL LKVIQVLNEL
250 260 270 280 290 300
VGSRGFGRVE HLENRVVGFK SREVYEVPAA LVLINSHKDL EKSTYTPLEF RFKRSLDGQW
310 320 330 340 350 360
SDLVYQGLWF EPLRETIQIA GDNLNKWISG EVFIEVENGN MKILGRKGKF SPFSEEIASY
370 380 390
NKGWYPSDEM ARGFIEIFGM HSLVARKSRG I