Q4J6M3

PR
Gene name
cutA (Saci_2271)
Protein name
Glyceraldehyde dehydrogenase large chain
Names
Glyceraldehyde dehydrogenase subunit A, Glyceraldehyde dehydrogenase subunit alpha
Species
Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
KEGG Pathway
sai:Saci_2271
EC number
1.2.99.8: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

249-318 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4J6M3

Entry ID Method Resolution Chain Position Source
AF-Q4J6M3-F1 Predicted AlphaFoldDB

No variants for Q4J6M3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4J6M3

No associated diseases with Q4J6M3

3 regional properties for Q4J6M3

Type Name Position InterPro Accession
domain Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead 18 - 136 IPR000674
domain Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain 151 - 394 IPR008274
domain Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain 422 - 684 IPR046867

Functions

Description
EC Number 1.2.99.8 With other acceptors
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
glyceraldehyde oxidoreductase activity Catalysis of the reaction: A + D-glyceraldehyde + H2O = (R)-glycerate + AH2 + H(+).
iron ion binding Binding to an iron (Fe) ion.
molybdopterin cofactor binding Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
oxidoreductase activity, acting on the aldehyde or oxo group of donors Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTYTGKSIKR LNDDKFITGR SNYIDDIKIP SLYAGFVRSP YPHAIIKRID ATDALKVNGI
70 80 90 100 110 120
VAVFSGKDIN PMLKGGVGVL SAYVNPSLFR FKERKAFPED NKVKYVGEPV AIVIGQDKYA
130 140 150 160 170 180
VRDAIDRVNV EYEQLKPVIK MEDAEKDEVI VHDELKTNVS YKIPFKAGDI EKAFSQADKV
190 200 210 220 230 240
VKVEAINERL IPNPMEPRGI LSVYDGNSLS VWYSTQVPHF ARSEFARIFG IPETKIRVAM
250 260 270 280 290 300
PDVGGAFGSK VHIMAEELAV IASSILLRRP VRWTATRSEE MLASEARSNV FTGEVAVKKD
310 320 330 340 350 360
GTVLGIKGKL LLDLGAYLTL TAGIQPTIIP VMIPGPYKVR DLEIESTAVY TTTPPITMYR
370 380 390 400 410 420
GASRPEATYI IERIMSTVAD ELGLDDVTIR ERNLIDQLPY TNPFGLRYDT GDYIRVFKDG
430 440 450 460 470 480
VAKLEYNELR KWAQQERSKG HRVGVGLAFY LEICSFGPWE YGEIKVDNKG NVLVITGTTP
490 500 510 520 530 540
HGQGTETAIA QIVADALQIP IEKIRVVWGD TDIVEGSFGT YGSRSLTIGG SAALKVAERV
550 560 570 580 590 600
LDKMKRAAAS YFNADVQEIR YENEEFSVKN DPSKKASWDE IASLATTKEP IVEKIYYEND
610 620 630 640 650 660
VTFPYGVHVA VVEVDDLGMA RVVEYRAYDD IGKVINPALA EAQIHGGGVQ GVGQALYEKA
670 680 690 700 710 720
IINENGQLSV TYADYYVPTA VEAPRFISYF ADKSHPSNYP TGTKGVGEAA LIVGPAAIIR
730 740
AIEDAVGARF TKTPTPPEEI YKAIMSKK