Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4IQM6

Entry ID Method Resolution Chain Position Source
AF-Q4IQM6-F1 Predicted AlphaFoldDB

No variants for Q4IQM6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4IQM6

No associated diseases with Q4IQM6

3 regional properties for Q4IQM6

Type Name Position InterPro Accession
domain GINS subunit, domain A 50 - 124 IPR021151
domain DNA replication complex GINS protein SLD5, C-terminal 167 - 221 IPR031633
domain GINS complex protein Sld5, alpha-helical domain 23 - 144 IPR038749

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
DNA-templated DNA replication A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDIDDILRQV DPSSHGVPSE ARDLQALTRL WVAERSAPEL LEWPTDGLFE RVNARIKTQI
70 80 90 100 110 120
EKVEDMTGDM DPKTNFALIV IQTELERYKF LMRSFLRARL AKIDKHTLHY LSSQELRDRL
130 140 150 160 170 180
SPTELSYATK HQALLHNHYL SSFLASFPQQ LQNLNDTAGN ISMIDSPDLD TAVFIRMLRD
190 200 210 220
KDVYGKGTDA DITLPATNGD VLIIRWSSAK HMVDVGDAEL V