Q4IPB3
Gene name |
CWC27 (FGRRES_00945, FGSG_00945) |
Protein name |
Peptidyl-prolyl isomerase CWC27 |
Names |
PPIase CWC27, Rotamase CWC27 |
Species |
Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) |
KEGG Pathway |
fgr:FGSG_00945 |
EC number |
5.2.1.8: Cis-trans isomerases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4IPB3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4IPB3-F1 | Predicted | AlphaFoldDB |
No variants for Q4IPB3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4IPB3 | |||||
No associated diseases with Q4IPB3
Functions
| Description | ||
|---|---|---|
| EC Number | 5.2.1.8 | Cis-trans isomerases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| spliceosomal complex | Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| peptidyl-prolyl cis-trans isomerase activity | Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0). |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| protein folding | The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
| protein peptidyl-prolyl isomerization | The modification of a protein by cis-trans isomerization of a proline residue. |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAIYNLEPQ | PTASVIIHTT | RGELSVELFA | KQAPLTCRNF | LQLALDGYYD | NTIFHRLVPG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FILQGGDPTG | TGNGGESIYD | GGAFSGDLDP | WPMDQRMGKN | AGPTGINFKD | EFHSRLKFNR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RGLLGSANES | RPDTNSSQFF | FTLDTAEELN | GKNTMFGRIA | GDTVYNLAKM | GEGEVDEATE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RPTYPVKIER | IEILINPFED | MKKRSRVAAV | APSKTTTTKD | KKKKRKGGKQ | LLSFGDDEGD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DEMPVLKKKK | FDPRIVMEAP | EEAPEQDEVR | SKPTKAKKER | ASEKRVSIAQ | EEQDNSDQTT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PREPPKEVRQ | KPAPPVKMEI | EDESPEPEAP | RKTALERANE | EMAALKASMR | RTIHSEEPVK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EKKKSALESM | IPETSMRGRK | RRPGAANTSA | ADDAKALRML | KAFQSRLEKA | PPEKENEPAA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RETTKDGEDA | QAGDEEAELC | DLHFIANCQS | CTSWDKQEKD | ESDDEGWMSH | ALSFAADKLG |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KDLSNRRKAE | EELVVIDPRE | KARTLKDEKK | AARDARQGNS | GRAWDQARDA | ARNAKMAQAA |
| SLAGRGAK |