Q4HYQ4
Gene name |
SPT6 (FGRRES_09904, FGSG_09904) |
Protein name |
Transcription elongation factor SPT6 |
Names |
Chromatin elongation factor SPT6 |
Species |
Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) (Wheat head blight fungus) (Fusarium graminearum) |
KEGG Pathway |
fgr:FGSG_09904 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4HYQ4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4HYQ4-F1 | Predicted | AlphaFoldDB |
No variants for Q4HYQ4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q4HYQ4 | |||||
No associated diseases with Q4HYQ4
10 regional properties for Q4HYQ4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | SH2 domain | 1215 - 1305 | IPR000980 |
| domain | S1 domain | 1100 - 1168 | IPR003029 |
| domain | Spt6 acidic, N-terminal domain | 39 - 130 | IPR028083 |
| domain | Helix-turn-helix DNA-binding domain of Spt6 | 291 - 411 | IPR028088 |
| domain | Transcription elongation factor Spt6, YqgF domain | 706 - 861 | IPR028231 |
| domain | Transcription elongation factor Spt6, helix-hairpin-helix motif | 863 - 972 | IPR032706 |
| domain | Spt6, SH2 domain, C terminus | 1309 - 1398 | IPR035018 |
| domain | Spt6, SH2 domain, N terminus | 1214 - 1299 | IPR035019 |
| domain | Spt6, SH2 domain | 1187 - 1396 | IPR035420 |
| domain | HHH domain 9 | 981 - 1017 | IPR041692 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| nucleobase-containing compound metabolic process | Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. |
| positive regulation of transcription elongation by RNA polymerase II | Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNSMRDLIS | GEAELDDEEE | DESFDERGGQ | RRHKNAVEDS | SEEEEDDDDE | EEARKVREGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IVDEDEDEDE | GGESDADVRP | LHKRKREHRD | REEEAQLDED | DLDLIGEQFG | ERPKPTTQSK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FKRLKRGTRD | EDRGNQRRGL | DDIFSDEEDD | AGEQRAYNNR | SSYRQADEFD | DFIEEDFPDD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PEELEQQRED | AEVARPRDRV | IGNIADTANL | DKDALDDMEA | IFGNGEDYDW | ALQMEEEEED |
| 250 | 260 | 270 | 280 | 290 | 300 |
| REREEQAIEL | KDVFEPSQLK | EKLLTDEDNE | IRFTDEPERF | QIDRKTFKSL | QLTAEQFKEE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ARWITNQLWP | KKGLASDLQS | PFGKAVGKVL | EFFIVDEVEV | PYVFQHRKDY | LLHTRKTRNP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| NRDDPDAPEY | VISADKLLNQ | DDLWKILELD | IKFRSFVDKR | NALEKTVDNL | KGMEIHDAMV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DEMIPEATTM | EELQDLQDYL | HFQYGQQLKD | LAALAGNLSL | TKRPGSKSNL | LERVRQGKAY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| GFVRAYGISA | DQLAKNALRH | GKKVTPDDDA | QYPMDLADSL | IDDVFSTGDQ | VISAARQMYS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EELFASPRMR | KHFRNSYYQA | AEISCRRTEK | GLRRIDDSHP | YYEIKYLQNQ | AIADLVHQPE |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LFLKMMKAEE | EGLVTIKLDM | PARYDFRQHL | YQEFESENFS | DRAEQWREER | KKVLDLAYPK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LEKIIAKNVK | EVIRTFCQDE | VLKMCREEYA | KRLDQAPYKP | KGMILGTTPR | VLVLSNGMSD |
| 730 | 740 | 750 | 760 | 770 | 780 |
| PARDPICWAW | VEEDGRVIEQ | GKLGNLARDE | RQREEFEELV | KRRRPDVIGV | SGWSAETTKL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| VRDLEGLVNE | KGLMGPEFED | PDTNDYRTEP | LEVVVVNDEV | ARLYKDSPRA | LAEHPSLNPI |
| 850 | 860 | 870 | 880 | 890 | 900 |
| TRYCVALARY | MQNPMKEYAA | LGKDVSSLSY | HPCQNLLPAD | KLAKYLDSAM | VDMVNLCGVD |
| 910 | 920 | 930 | 940 | 950 | 960 |
| INEAMNDTYT | ANLLPYVSGL | GPRKATSVIK | AINANGGAVG | TRDELVGDPD | SGKLPVVGPR |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| VWNNCASFLF | IEYEATNPSS | DPLDNTRVHP | EDYELGRKMA | ADALELDEED | VKGETDENGP |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| GAIVRKLFKM | DEQDKVNELV | LEEYAEQLER | NYSQRKRATL | ETIRAELQAP | YEELRRNFAL |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| LSASEIFTMF | TGETKHTLCE | GMIVPVNVRV | VKDDFAIVKL | DCGIEGRVEG | HEVSHRSSIK |
| 1150 | 1160 | 1170 | 1180 | 1190 | 1200 |
| EVLSSGQTSQ | AKILDINYKD | FMAKLSMRED | ALRIPYKRPI | NLGRDGWDYV | LEAADKEELR |
| 1210 | 1220 | 1230 | 1240 | 1250 | 1260 |
| EKDKTTGRTQ | RVVKHPNFKP | FNGLQAEEYL | GSQPNGEVVI | RPSSKGNDHL | AVTWKVADGV |
| 1270 | 1280 | 1290 | 1300 | 1310 | 1320 |
| FQHIDVLEMQ | KETEFAVGKL | LRVGGKYTYT | DLDELIVEHV | KAMARKVEEL | MRHDKYQNRS |
| 1330 | 1340 | 1350 | 1360 | 1370 | 1380 |
| RGETEKWLTT | YIDANPNRST | YAFCIDTKHP | GYFWLCFKAS | RAAKVIALPV | RAIPQGFELK |
| 1390 | 1400 | ||||
| GYQYPDMRAL | CNGFKLRYQN | EFSKMGQR |