Q4FU86

PR
Gene name
dapE
Protein name
Succinyl-diaminopimelate desuccinylase
Names
SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Species
Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
KEGG Pathway
par:Psyc_0561
EC number
3.5.1.18: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4FU86

Entry ID Method Resolution Chain Position Source
AF-Q4FU86-F1 Predicted AlphaFoldDB

No variants for Q4FU86

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4FU86

No associated diseases with Q4FU86

3 regional properties for Q4FU86

Type Name Position InterPro Accession
domain Dihydrodipicolinate reductase, N-terminal 3 - 118 IPR000846
domain Dihydrodipicolinate reductase, C-terminal 121 - 255 IPR022663
conserved_site Dihydrodipicolinate reductase, conserved site 140 - 157 IPR022664

Functions

Description
EC Number 3.5.1.18 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
cobalt ion binding Binding to a cobalt ion (Co).
succinyl-diaminopimelate desuccinylase activity Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDIDNNLTS QTHQQATHQQ ETLDLSIALL ERPSVTPNDD GCQDILSERL TQAGFDCEFM
70 80 90 100 110 120
YYGDRQAKGE HAEVKNLWAR RGTSNPVICF AGHTDVVPTG DEKNWTYPPF TPTIADGYLW
130 140 150 160 170 180
ARGAADMKTG IAAFTIAAER FVANHPQHNG SIAFLITSDE EGPSINGTVK VIETLEARQE
190 200 210 220 230 240
KITYCLVGEP SSTDTLGDII KNGRRGSLGA VLTVTGKQGH VAYPHLASNP IHAAMSALSE
250 260 270 280 290 300
LTNASWDNGN DYFPATSLQI SNINGGTGAT NVIPETLEVV FNFRFSTETT EDELKAKTHA
310 320 330 340 350 360
IFDKYFKDSK AKYDIHWKLS GQPFLTPEGK LVSACQQAIK SVTGTDTTLS TSGGTSDGRF
370 380 390 400
IAPTGAQVVE LGVRNATIHQ VDEKVEVDDL GRLAQIYERI LENLLLD