Q4FTK9

PR
Gene name
gcvP
Protein name
Glycine dehydrogenase (decarboxylating)
Names
Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring)
Species
Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
KEGG Pathway
par:Psyc_0796
EC number
1.4.4.2: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

707-781 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q4FTK9

Entry ID Method Resolution Chain Position Source
AF-Q4FTK9-F1 Predicted AlphaFoldDB

No variants for Q4FTK9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4FTK9

No associated diseases with Q4FTK9

3 regional properties for Q4FTK9

Type Name Position InterPro Accession
domain Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic 7 - 293 IPR006075
conserved_site Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site 148 - 162 IPR017958
domain Asn/Gln amidotransferase 332 - 479 IPR018027

Functions

Description
EC Number 1.4.4.2 With a disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
glycine dehydrogenase (decarboxylating) activity Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.

1 GO annotations of biological process

Name Definition
glycine decarboxylation via glycine cleavage system The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTISQNPTLD TFKGLFNEAE FVYRHLGSND AKQADLLSAI GYKDMATFIN DTVPEPVRLH
70 80 90 100 110 120
KELDLPVAMS EHAALAKLRT MADDITVNKS YIGQGYSPVR MPAVIQRNVL ENPGWYTAYT
130 140 150 160 170 180
PYQAEIAQGR LEALLNFQQV CIDLTGLELA GASLLDEATA AAEAMAMSKR VSKSKSMQFF
190 200 210 220 230 240
VDDRVYSQTL DVINTRAKYF GWEVVVGDFE LAKSGDYFGA LFQYVGVEGD VKDLTDVIAA
250 260 270 280 290 300
VKKNKTYVNV VSDIMSLVLL KSPADMGADV ALGSTQRFGI PMGFGGPHAA YFAFSDKAKR
310 320 330 340 350 360
SAPGRIIGVS KDSQGNTALR MALQTREQHI RREKANSNIC TSQVLLANLA GMYAVYHGPG
370 380 390 400 410 420
GVKRIATRIH AFATAFADVI KNANDSNLNV VHDQFFDSVV IDCGSEKLAT QIFENADNVG
430 440 450 460 470 480
YNLWRLGDSK LSVAFSETSD QEDFKILTQL FVTKAHDLPE DARISLDSTH LRTDDILTHP
490 500 510 520 530 540
VFNSHHTEHE MLRYLKSLED KDLAMNRSMI SLGSCTMKLN ATSEMLPITW PEFANVHPFA
550 560 570 580 590 600
PRDQVTGYVA MIDSLQEQLK AITGFDDVSM QPNSGASGEY AGLLAIRRYH ESLGETDRDV
610 620 630 640 650 660
CLIPMSAHGT NPATAMMMGM KVVVVKTDDN GNVDIDDLTA KSEEHSARLG ALMITYPSTH
670 680 690 700 710 720
GVFEEGIRKI CDLIHKHGGQ VYMDGANMNA QVGMMQPADV GADVLHMNLH KTFCIPHGGG
730 740 750 760 770 780
GPGMGPIGMK SHLAPFMANH TLSPVHNAQK DCSAVSAAPY GSASILPISW MYIAMMGRDG
790 800 810 820 830 840
LLKATELALL NANYVAAELK DYYPVLYTGK NGRVAHECII DIRPLKEETG ISESDIAKRL
850 860 870 880 890 900
MDYGFHSPTM SFPVAGTLMI EPTESESKEE LDRFISALKS IKAEAMKAKA GEDNWTLENN
910 920 930 940 950 960
PLVNAPHTAA MVIDGEWTYP YSRETAAFPL PYIRTNKFWP SVARVDDAYG DKNLMCSCPS
IENYM