Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q4A9A2

Entry ID Method Resolution Chain Position Source
AF-Q4A9A2-F1 Predicted AlphaFoldDB

No variants for Q4A9A2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q4A9A2

No associated diseases with Q4A9A2

5 regional properties for Q4A9A2

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 111 - 278 IPR000795
domain Small GTP-binding protein domain 116 - 269 IPR005225
domain Translation initiation factor IF-2, N-terminal 36 - 83 IPR006847
domain Translation initiation factor IF- 2, domain 3 379 - 491 IPR023115
domain Translation initiation factor IF-2, domain II 287 - 381 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKSQKRISN VSEIKAQLKT VETKVHNGVF LFSGIMTIAE LAQKINVSVN QIITYFFHQA
70 80 90 100 110 120
KMYNLNHSLS EDEIAEICLE FGLDFKKEVQ IDASNFMEEV SILDQDKDLS PRPPIITVMG
130 140 150 160 170 180
HVDHGKTTLL DYIRKTNIAK NEKGGITQHT GAYQVVFQGH IINFIDTPGH EAFTQMRARG
190 200 210 220 230 240
AKVTDIIVLV VAADDGVMPQ TKEAINHAAA ANVPIIVFVN KMDKPNKDVD RIKNELSALN
250 260 270 280 290 300
IVTEEWGGSN IFVYGSALTG QGIDTLFSSI LLLAEILELK ANKNRYPIGT VIEAKLHHNK
310 320 330 340 350 360
GTIATLMVQN GTLMVRDFIV AGYQYGRIRS LENTNGQPIK FAPPGTPVIV TGLNYVPEAG
370 380 390 400 410 420
DKFFGFHEEK FAKQLALERK QSEKISKTKV QTKQQTKEKT LNIIIKADVA GIAQALHSTI
430 440 450 460 470 480
EKLASKQVHI HILHSGVGIV NKADILLAQT SNSIIYAFNL QIPAAIKAQA KQAQVEIREH
490 500 510 520 530 540
TIIYKIVDEI KKQVRGMREI RYELQQIGTA KIIAKFWFSK VGSIAGCSVL SGKFVENCKI
550 560 570 580 590
ELWRNSKLIH SGKIESLQRD KNPVKEVQVG NEFGTHIYKF NDIEIGDELK AFLDVEIEE