Q49Z29

PR
Gene name
cshA
Protein name
DEAD-box ATP-dependent RNA helicase CshA
Names
Species
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)
KEGG Pathway
ssp:SSP0802
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q49Z29

Entry ID Method Resolution Chain Position Source
AF-Q49Z29-F1 Predicted AlphaFoldDB

No variants for Q49Z29

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q49Z29

No associated diseases with Q49Z29

2 regional properties for Q49Z29

Type Name Position InterPro Accession
binding_site Copper centre Cu(A) 251 - 305 IPR001505
domain Cytochrome c oxidase subunit II-like C-terminal 147 - 323 IPR002429

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

2 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
RNA secondary structure unwinding The process in which a secondary structure of RNA are broken or 'melted'.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQNFKELGIS DKMAETLQSM GFNEATPIQK ESIPLALEGK DVLGQAQTGT GKTGAFGIPL
70 80 90 100 110 120
IEKVADQEGV QSLILAPTRE LAMQVAESLK AFAKGQNIQV VTVFGGMPID RQIKALKKGP
130 140 150 160 170 180
QIVVGTPGRV IDHLNRRTLK TNDIHTLILD EADEMMNMGF IDDMKFIMDK IPAEQRQTML
190 200 210 220 230 240
FSATMPKAIQ TLVQQFMKSP VIVKTMNNEM SDPQIEEYYT IVKELEKFDT FTSFLDVHQP
250 260 270 280 290 300
ELAIVFGRTK RRVDELTSAL ISKGYKAEGL HGDITQAKRL EVLKKFKNDQ LDILVATDVA
310 320 330 340 350 360
ARGLDISGVS HVYNFDIPQD TESYTHRIGR TGRAGKKGVA ITFVNPIEMD YIRQIEQANK
370 380 390 400 410 420
RQMTALRPPH RKEVLKAREN DIKGKVQNWM SRDNEPRLQR IATELLGEYN DVDLIASLLQ
430 440 450 460 470 480
ELVESNDEVD VQLTFEKPLS RGKGRQGKGG PKRGGNHKRG GGKFDNKNRR SGKGGFNNKK
490 500
KNDRPSSDRN NNKKSMKGRT FADHKK