Q49WH7

PR
Gene name
pgcA (SSP1737)
Protein name
Phosphoglucomutase
Names
PGM, Alpha-phosphoglucomutase, Glucose phosphomutase
Species
Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)
KEGG Pathway
ssp:SSP1737
EC number
5.4.2.2: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q49WH7

Entry ID Method Resolution Chain Position Source
AF-Q49WH7-F1 Predicted AlphaFoldDB

No variants for Q49WH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q49WH7

No associated diseases with Q49WH7

2 regional properties for Q49WH7

Type Name Position InterPro Accession
domain NodB homology domain 102 - 349 IPR002509
domain Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal 318 - 645 IPR032772

Functions

Description
EC Number 5.4.2.2 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoglucomutase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.

2 GO annotations of biological process

Name Definition
enterobacterial common antigen biosynthetic process The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKALWLENIN ESLVKDFYET QTEEEQNAGF EGVLSFGTAG IRSTFGLGPA RLNAFTVRKV
70 80 90 100 110 120
ALGLAQYLNH NVDDASVVIH FDTRFLSKAF SQEMASVLAN NGITAIISDN YKSTPELSFA
130 140 150 160 170 180
VRHLQVNAGI MITASHNPKN YNGIKIYNEK GGQLLPEASE QLSEYINSIE TPLNIEKGDF
190 200 210 220 230 240
NAFVENGKIK YMSNEVTESY KKEVKSLVGS IDAHDAKVIL TSLHGTSLPL VSDILTELDY
250 260 270 280 290 300
HNFVIEKEQS EPNGNFPTVA IANPEDEAAF TLGKQLADKT DAQLIIATDP DADRLGFIER
310 320 330 340 350 360
YGDNDFRYFN GNEIGLLLMK LRFQDLTEDS TPQYMIKSIV TSELAERLAT SLNVEVNDVL
370 380 390 400 410 420
TGFKFISDLI EHKQKDDDKQ LLLAFEESHG YLAQPISRDK DAIQMVPLLV KYKNLLDKNG
430 440 450 460 470 480
ITFKETIEDI YENIGYFKDR TLAPTFEGKA GVKKIESIMS QFRNEQVFSI CGMDVLKIED
490 500 510 520 530 540
YHVGEVRDMI TGHTEKLTLP KTNLIRFIFE NGFIALRPSG TEPKIKLYFS LEVENIDEIT
550
QQFEANYINN IV