Q497M3

PR
Gene name
Apobec4
Protein name
Putative C->U-editing enzyme APOBEC-4
Names
Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

223-374 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q497M3

Entry ID Method Resolution Chain Position Source
AF-Q497M3-F1 Predicted AlphaFoldDB

26 variants for Q497M3

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3388502030 28 C>Y No EVA
rs3388507498 41 A>G No EVA
rs3388506201 43 V>G No EVA
rs3388508782 46 T>I No EVA
rs253908267 89 S>T No EVA
rs3388507479 93 P>R No EVA
rs3388506193 147 V>F No EVA
rs3388504108 151 V>I No EVA
rs230111729 163 F>Y No EVA
rs250059349 164 P>T No EVA
rs212292207 165 T>S No EVA
rs217018962 171 K>E No EVA
rs231770988 214 I>T No EVA
rs216012332 225 T>A No EVA
rs238207091 239 T>I No EVA
rs262687160 243 L>P No EVA
rs222829040 246 Q>R No EVA
rs237494742 265 S>N No EVA
rs3390795773 268 P>L No EVA
rs49502638 268 P>T No EVA
rs3390806094 288 V>G No EVA
rs260336369 295 P>L No EVA
rs245195728 325 V>L No EVA
rs265289824 327 K>N No EVA
rs229712670 342 E>G No EVA
rs31839828 343 S>T No EVA

No associated diseases with Q497M3

11 regional properties for Q497M3

Type Name Position InterPro Accession
repeat Leucine-rich repeat 93 - 114 IPR001611-1
repeat Leucine-rich repeat 116 - 174 IPR001611-2
repeat Leucine-rich repeat, typical subtype 91 - 114 IPR003591-1
repeat Leucine-rich repeat, typical subtype 115 - 138 IPR003591-2
repeat Leucine-rich repeat, typical subtype 139 - 162 IPR003591-3
repeat Leucine-rich repeat, typical subtype 163 - 186 IPR003591-4
repeat Leucine-rich repeat, typical subtype 190 - 214 IPR003591-5
domain Immunoglobulin subtype 2 300 - 369 IPR003598
domain Immunoglobulin subtype 294 - 380 IPR003599
domain Immunoglobulin-like domain 302 - 378 IPR007110
domain Immunoglobulin 298 - 367 IPR013151

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
mRNA processing Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEPLYEEILT QGGTIVKPYY WLSLSLGCTN CPYHIRTGEE ARVPYTEFHQ TFGFPWSTYP
70 80 90 100 110 120
QTKHLTFYEL RSSSKNLIQK GLASNCTGSH NHPEAMLFEK NGYLDAVIFH NSNIRHIILY
130 140 150 160 170 180
SNNSPCNEAK HCCISKMYNF LMNYPEVTLS VFFSQLYHTE KQFPTSAWNR KALQSLASLW
190 200 210 220 230 240
PQVTLSPICG GLWHAILEKF VSNISGSTVP QPFIAGRILA DRYNTYEINS IIAAKPYFTD
250 260 270 280 290 300
GLLSRQKENQ NREAWAAFEK HPLGSAAPAQ RQPTRGQDPR TPAVLMLVSN RDLPPIHVGS
310 320 330 340 350 360
TPQKPRTVVR HLNMLQLSSF KVKDVKKPPS GRPVEEVEVM KESARSQKAN KKNRSQWKKQ
370
TLVIKPRICR LLER