Q493T3

PR
Gene name
pnp
Protein name
Polyribonucleotide nucleotidyltransferase
Names
Polynucleotide phosphorylase, PNPase
Species
Blochmannia pennsylvanicus (strain BPEN)
KEGG Pathway
bpn:BPEN_112
EC number
2.7.7.8: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

49-120 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q493T3

Entry ID Method Resolution Chain Position Source
AF-Q493T3-F1 Predicted AlphaFoldDB

No variants for Q493T3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q493T3

No associated diseases with Q493T3

9 regional properties for Q493T3

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 19 - 144 IPR001247-1
domain Exoribonuclease, phosphorolytic domain 1 326 - 458 IPR001247-2
domain S1 domain 621 - 692 IPR003029
domain K Homology domain 554 - 619 IPR004087
domain K Homology domain, type 1 558 - 615 IPR004088
domain Exoribonuclease, phosphorolytic domain 2 147 - 210 IPR015847-1
domain Exoribonuclease, phosphorolytic domain 2 462 - 530 IPR015847-2
domain Polyribonucleotide nucleotidyltransferase, RNA-binding domain 244 - 322 IPR015848
domain RNA-binding domain, S1 622 - 692 IPR022967

Functions

Description
EC Number 2.7.7.8 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
polyribonucleotide nucleotidyltransferase activity Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
RNA binding Binding to an RNA molecule or a portion thereof.

2 GO annotations of biological process

Name Definition
mRNA catabolic process The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLDPIIHKFK YGQHTVILDI GTIARQANAA VMVSMSDTTV LVTVVSSNQV RLEQDFFPLV
70 80 90 100 110 120
VNYQERTYAA GKFPGGFFRR EGRPSENETL TSRLIDRPIR PLFPKGFIND VQVVATVVSV
130 140 150 160 170 180
NPQVNPDIVA IIGVSAALSL SDIPFFGPIG AARVGYIKNQ YVLNPTTTEL SNSKLDLVIS
190 200 210 220 230 240
GTESNILMVE SESCLLSEKE ILDAIIFGHE QQQIVIHNIN KLVKKVGKTK YSWNEKEVNI
250 260 270 280 290 300
SLKTYLSELY ESRAQDIYCF FDKKERHAQV DSIKKDIVKT VLNSYQHAAV DEKEIMYLLN
310 320 330 340 350 360
YLEAQSIRYR ILTNKLRIDG RSQDTIRKID IKTGILPRTH GSALFTRGDT QALVAVTLGT
370 380 390 400 410 420
ERDAQNIDGL TGIRVDRFLL HYNFPPYCVG EIGVIGAPKR REIGHGRLAK RGMLAVMPNA
430 440 450 460 470 480
NEFPYTIRVV SEITESNGSS SMASICGTSL ALMDAGVPIK AAVAGVAMGL IKEGNDFVVL
490 500 510 520 530 540
SDIVSDEDHI GDMDFKVSGS RQGITALQMD IKTDGITYDI INIALKKAKN ARLQILDVME
550 560 570 580 590 600
QIIKFPNQEI SKFAPRIYSI KVNPDKIKDV IGKGGSVIRS LTEETNTIID IEDNGIIKIV
610 620 630 640 650 660
ALDYDKAKQA IRRINDITAN VEIGAVYTGK VSHIVEFGAF VTILSGKEGL VHISQISERR
670 680 690
INKVTDYLKL GQKVLVKVLE IDRQGRIRLS MKGVHQVSA