Q49173

PR
Gene name
mrtG (mcrIIG, Mfer_0733)
Protein name
Methyl-coenzyme M reductase II subunit gamma
Names
MCR II gamma, Coenzyme-B sulfoethylthiotransferase gamma
Species
Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S)
KEGG Pathway
mfv:Mfer_0733
EC number
2.8.4.1: Transferring alkylthio groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-103 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q49173

Entry ID Method Resolution Chain Position Source
AF-Q49173-F1 Predicted AlphaFoldDB

No variants for Q49173

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q49173

No associated diseases with Q49173

4 regional properties for Q49173

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 382 - 618 IPR003439
domain AAA+ ATPase domain 408 - 581 IPR003593
domain ABC transporter type 1, transmembrane domain 67 - 349 IPR011527
conserved_site ABC transporter-like, conserved site 521 - 535 IPR017871

Functions

Description
EC Number 2.8.4.1 Transferring alkylthio groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
coenzyme-B sulfoethylthiotransferase activity Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.

1 GO annotations of biological process

Name Definition
methanogenesis The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAYEPQFNPG ETKIAENRRK HMNPNYELKK LREIADEDIV RVLGHRSPGE SFKTVHPPLE
70 80 90 100 110 120
EMDFEEDPMK DIVEPIEGAK QGTRIRYIQF ADSMYNAPAQ PYDRARTYMW RFRGVDTGTL
130 140 150 160 170 180
SGRQVIEMRE LDLEKVSKIL LETEIFDPAR CGIRGATVHG HSLRFDENGL MFDALQRYIY
190 200 210 220 230 240
DEDSGHVVYV KDQVGRPLDQ PVDMGEPLPE DELKEITTIY RKDNIGMRED EELLEVVNKI
250 260
HEARTIGGFG MEVFKKDLNK RLGGANE