Q49110

PR
Gene name
pdhC (odp2, MCAP_0227)
Protein name
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
Names
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2
Species
Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343 / NCTC 10154)
KEGG Pathway
mcp:MCAP_0227
EC number
2.3.1.12: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

51-245 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q49110

Entry ID Method Resolution Chain Position Source
AF-Q49110-F1 Predicted AlphaFoldDB

No variants for Q49110

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q49110

No associated diseases with Q49110

3 regional properties for Q49110

Type Name Position InterPro Accession
domain Biotin/lipoyl attachment 2 - 77 IPR000089
domain 2-oxoacid dehydrogenase acyltransferase, catalytic domain 153 - 381 IPR001078
binding_site 2-oxo acid dehydrogenase, lipoyl-binding site 27 - 56 IPR003016

Functions

Description
EC Number 2.3.1.12 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
dihydrolipoyllysine-residue acetyltransferase activity Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.

1 GO annotations of biological process

Name Definition
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKVKFADIG EGLTEGTVAE VLVKVGDVVK EGQSLYFVET DKVNSEIPAP VAGKIAVINI
70 80 90 100 110 120
KAGQEIKVGD VVMEIEDGSD TSATSEPKAE TKSEAKVEVV EENASVVGAT PVSNDVIVRK
130 140 150 160 170 180
QTTTVNKSST IKATPLARKV AADLNIDLSL VTPTGPNQRI LVADIKNHQA SSTQLASQPI
190 200 210 220 230 240
SQPAPTPSPS AHQTIAPTIK VVEPSAPLSW DEVPMNGVRK ATVKAMTKSH TEIAAFTGMK
250 260 270 280 290 300
NTDITETHKM RTELKDHAAA SGIKLTYLAF IIKAVAKSLR DMPNINVRGD FANNKIQFMH
310 320 330 340 350 360
NINIGIAVDT PNGLMVPVIK GADHLSVFEI AIKISELANK AKDGKLTRAE MTEATFTVSN
370 380 390 400 410 420
FGSVGLDYAT PIINSPESAI LGVGTMSQTP LYINGELQKR FIMPLSMTCD HRIIDGADAG
430
RFLIKVQDYL SKPVLLFM