Q48TP4

PR
Gene name
potA
Protein name
Spermidine/putrescine import ATP-binding protein PotA
Names
Species
Streptococcus pyogenes serotype M28 (strain MGAS6180)
KEGG Pathway
spb:M28_Spy0803
EC number
7.6.2.11: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

85-163 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q48TP4

Entry ID Method Resolution Chain Position Source
AF-Q48TP4-F1 Predicted AlphaFoldDB

No variants for Q48TP4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q48TP4

No associated diseases with Q48TP4

4 regional properties for Q48TP4

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 6 - 238 IPR003439
domain AAA+ ATPase domain 32 - 215 IPR003593
domain Transport-associated OB, type 2 276 - 344 IPR013611
conserved_site ABC transporter-like, conserved site 138 - 152 IPR017871

Functions

Description
EC Number 7.6.2.11 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.

2 GO annotations of molecular function

Name Definition
ABC-type polyamine transporter activity Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKPIITFNN VSKTFEDSGT QVLKNINFDL EEGKFYTLLG ASGSGKSTIL NIMAGLLDAS
70 80 90 100 110 120
SGDIYLDGER INDLPINKRD IHTVFQNYAL FPHMTVFENV AFALKLKKVD KKEIAKRVKE
130 140 150 160 170 180
TLKMVQLEGY ENRSIQKLSG GQRQRVAIAR AIINQPRVVL LDEPLSALDL KLRTEMQYEL
190 200 210 220 230 240
RELQQRLGIT FVFVTHDQEE ALAMSDWVFV MNEGEIVQSG TPVDIYDEPI NHFVANFIGE
250 260 270 280 290 300
SNIINGTMIE DYLVSFNGKE FESVDGGMRP NEPVEVVIRP EDLQITLPEE GKLQVKVDTQ
310 320 330 340 350 360
LFRGVHYEII AYDELGNEWM IHSTRKAIEG EVIGLDFTPE DLHIMRLNET EEEFDARIEE
370 380
YVEMDEPEDG LINAIEEERN EENL