Q48AN2
Gene name |
pyrE |
Protein name |
Orotate phosphoribosyltransferase |
Names |
OPRT, OPRTase |
Species |
Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio psychroerythus) |
KEGG Pathway |
cps:CPS_0113 |
EC number |
2.4.2.10: Pentosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q48AN2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q48AN2-F1 | Predicted | AlphaFoldDB |
No variants for Q48AN2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q48AN2 | |||||
No associated diseases with Q48AN2
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.2.10 | Pentosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| orotate phosphoribosyltransferase activity | Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' UMP biosynthetic process | The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKDYQREFIE | FAIEKQVLRF | GEFTLKSGRV | SPYFFNAGMF | KTGGDLARLG | RFYAATLMDA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KIDFDLVFGP | AYKGIPIATT | TTVALYDHHN | VDVPYCFNRK | EAKTHGEGGS | LVGAELEGKI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLVDDVITAG | TAIRESMEII | KAHGAQLSGV | LIALDRQEKG | QGQLSAIQEV | ERDFGTQVAA |
| 190 | 200 | 210 | 220 | ||
| IVTLGDVVTY | LEEKLEGKVA | NQPELAENLA | SIKKYRLNYG | I |