Q47RM6
Gene name |
Tfu_0853 |
Protein name |
Trans,polycis-polyprenyl diphosphate synthase ((2Z,6E)-farnesyl diphosphate specific) |
Names |
Cis-prenyltransferase, Dodecaprenyl diphosphate synthase |
Species |
Thermobifida fusca (strain YX) |
KEGG Pathway |
tfu:Tfu_0853 |
EC number |
2.5.1.88: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q47RM6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 7CPM | X-ray | 260 A | A/B/C/D/E/F | 1-282 | PDB |
| 7CPN | X-ray | 228 A | A/B/C/D/E/F | 1-282 | PDB |
| AF-Q47RM6-F1 | Predicted | AlphaFoldDB |
No variants for Q47RM6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q47RM6 | |||||
No associated diseases with Q47RM6
1 regional properties for Q47RM6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Di-trans-poly-cis-decaprenylcistransferase-like, conserved site | 208 - 225 | IPR018520 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.88 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| prenyltransferase activity | Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSPKTVFSTD | THREPIPPQP | HPSGARPPQL | PRELIPRHVA | IVMDGNGRWA | KQRGLPRTEG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HKAGESSLFD | VIEGALELGV | PYLSAYAFST | ENWKRSPDEV | RFLMGFNRDV | IRRRRDELHA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RGVRVRWAGR | PGRLWKSVIK | ELTEAEELTK | HNTKLTLQFC | VNYGGRAEIA | DAAAALARDV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AAGRLSPNRV | TEATLARYLY | HPDIPDVDLF | IRSSGEQRLS | NFLLWQSSYA | EFVFLDTLWP |
| 250 | 260 | 270 | 280 | ||
| DFDRRHFWQA | CEIYARRDRR | YGGAEPNPVG | PPQSAAGAQG | QD |