Q47NX7

PR
Gene name
arc
Protein name
Proteasome-associated ATPase
Names
AAA ATPase forming ring-shaped complexes, ARC, Proteasomal ATPase
Species
Thermobifida fusca (strain YX)
KEGG Pathway
tfu:Tfu_1809
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-83 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q47NX7

Entry ID Method Resolution Chain Position Source
AF-Q47NX7-F1 Predicted AlphaFoldDB

No variants for Q47NX7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q47NX7

No associated diseases with Q47NX7

5 regional properties for Q47NX7

Type Name Position InterPro Accession
domain AAA+ ATPase domain 261 - 415 IPR003593
domain ATPase, AAA-type, core 265 - 413 IPR003959
conserved_site ATPase, AAA-type, conserved site 383 - 401 IPR003960
domain Proteasomal ATPase OB C-terminal domain 154 - 210 IPR032501
domain Proteasomal ATPase, N-terminal OB domain 94 - 153 IPR041626

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
proteasome complex A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
modification-dependent protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
proteasomal protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADRDDERHA ERDRDELVAQ VSYLEKELSV LRRKLADSPR HVRLLEDRLQ EAQTALAAAN
70 80 90 100 110 120
AKNERLVSAL KEARDQIVAL KEEVDRLSQP PSGFGVFLRA RDDGTVEIFT NGRKMRVNVS
130 140 150 160 170 180
PSVNVDELRP GQEVMLNEAF NVVEASSYET VGEVVMLKEI LEDGERVLVI SNHDEERIVR
190 200 210 220 230 240
IAEPLRDEPL RAGDSLLLEP RSGYVYERIP KAEVEELILE EVPDISYSDI GGLNGQIEMI
250 260 270 280 290 300
RDAVELPYLH KELFREHKLR PPKGVLLYGP PGCGKTLIAK AVANSLAKQV AEKTGRDVGK
310 320 330 340 350 360
SFFLNIKGPE LLNKYVGETE RHIRLVFQRA REKASEGTPV IVFFDEMDSI FRTRGSGVSS
370 380 390 400 410 420
DVENTIVPQL LSEIDGVEGL ENVIVIGASN REDMIDPAIL RPGRLDVKIK IERPDAEAAR
430 440 450 460 470 480
DIFSKYITPD LPLHPDDLAE HGGSPTATVN AMIQRVVERM YAETEENRFL EVTYANGDKE
490 500 510 520 530 540
VLYFKDFNSG AMIQNIVDRA KKMAIKDYLE NGSKGLRVSH LLQACVDEFS ENEDLPNTTN
550 560 570 580
PDDWARISGK KGERIVYIRT LVSGKKGADA GRSIDTVANT GQYL