Q47IT5
Gene name |
folE2-1 |
Protein name |
GTP cyclohydrolase FolE2 1 |
Names |
|
Species |
Dechloromonas aromatica (strain RCB) |
KEGG Pathway |
dar:Daro_0489 |
EC number |
3.5.4.16: In cyclic amidines |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q47IT5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q47IT5-F1 | Predicted | AlphaFoldDB |
No variants for Q47IT5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q47IT5 | |||||
No associated diseases with Q47IT5
3 regional properties for Q47IT5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | GTP cyclohydrolase I, conserved site | 98 - 114 | IPR018234-1 |
| conserved_site | GTP cyclohydrolase I, conserved site | 146 - 156 | IPR018234-2 |
| domain | GTP cyclohydrolase I domain | 41 - 218 | IPR020602 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.5.4.16 | In cyclic amidines |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP cyclohydrolase I activity | Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 7,8-dihydroneopterin 3'-triphosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNAPENIFLP | DVQAAADTRR | LAIQSVGVKG | LRYPLQLENA | AGELTSTVAT | FAMSVGLPPE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VKGTHMSRFV | ELLEARTGPL | TQVGLLRMMA | DMLLRLDASS | GRIELAFPYF | IRKMAPVSGV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESLLDYDATL | IVDQRAWESA | TLTLRVVAPV | TSLCPCSKKI | SDYGAHNQRS | HITLEARLRS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PMSIEDLVRI | AEEEASCEVF | GLLKRPDEKW | VTERAYDNPK | FVEDLVRDIA | LRLMNEPRIA |
| 250 | 260 | ||||
| EWKVASENFE | SIHNHSAYAE | LYGCNE |