Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q47D94

Entry ID Method Resolution Chain Position Source
AF-Q47D94-F1 Predicted AlphaFoldDB

No variants for Q47D94

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q47D94

No associated diseases with Q47D94

7 regional properties for Q47D94

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 404 - 571 IPR000795
domain Small GTP-binding protein domain 407 - 562 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 327 - 377 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 60 - 97 IPR013575
domain Translation initiation factor IF- 2, domain 3 680 - 794 IPR023115
domain Translation initiation factor IF-2, domain II 579 - 673 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSATTVSQFA VELKMPVVAL LEQLGKAGVG KSDANDMLND QDKTRLLDYL RRAHGDESQT
70 80 90 100 110 120
KITLTRKQTS EIKATDSHGR ARTVQVEVRK KRVLVKRDIG EHAPEVELEA SNALQEEVSA
130 140 150 160 170 180
PEVIPEPVVE VVPEPVIEVV PEPVVEIVPE PVVEAPVEVP VEEVVLEKAA PVAPTRASII
190 200 210 220 230 240
GEKELQARAE ESRRYNQLRE IQERELREKQ AREAQLVQMR QQAELAAAAA KAAELAKNQA
250 260 270 280 290 300
ATQAKTSEGA EKGTLHKKPE TPGKKGDKGG RAADDGKKKG GIKTRGSDGA GGWKDNRHGH
310 320 330 340 350 360
KKSHKVDDGQ GSFQAPTEPV VREVHIPETI SVSDLAHKMA IKATEIIKVM MKMGSMVTIN
370 380 390 400 410 420
QVLDQETAMI VVEEMGHQAL AAKLDDPDAF LEEHAEHKDV PLEHRAPVVT VMGHVDHGKT
430 440 450 460 470 480
SLLDYIRRAK VASGEAGGIT QHIGAYHVET DRGMVTFLDT PGHEAFTAMR ARGAKATDIV
490 500 510 520 530 540
ILVVAADDGV MPQTKEAIHH AKAAGVPLVV AVNKIDKPDA NPERVKQELV AEGVIPEEYG
550 560 570 580 590 600
GDSPFVPVSA KKGTGIDELL EQVLLQAEIL ELTAQKDAPA KGLIIEARLD KGRGAVATML
610 620 630 640 650 660
VQSGTLKRGD IVLAGQVFGR VRAMLDENGK PINEAGPSIP VEILGLSDVP AAGEEAIVLG
670 680 690 700 710 720
DEKKAREIAL FRQGKFRDVK LAKQQAAKLE NMFQQMEEGE VKTLPLIVKA DVQGSQEALV
730 740 750 760 770 780
QTLSKLSNEE VRVQIIHGAV GAISESDVNL AQASGAVIIG FNIRADAGSR KLAESFGVDI
790 800 810 820 830 840
RYYNVIYDAV DEVKAALSGM LSPEKREQIT GMVEIRQVFL VSKVGAIAGC YVLEGFVKRN
850 860 870 880 890 900
SRVRLLRNNV VQWDGELDSL KRFKDDVKEV RSNFECGLSL RGNNDIQVGD QLEVYEIQEV
ARSL