Q47319

PR
Gene name
tapT
Protein name
tRNA-uridine aminocarboxypropyltransferase
Names
SAM-dependent 3-amino-3-carboxypropyl transferase, tRNA U47 acp transferase A, tRNA aminocarboxypropyltransferase
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2583
EC number
2.5.1.25: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

186-232 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q47319

Entry ID Method Resolution Chain Position Source
AF-Q47319-F1 Predicted AlphaFoldDB

No variants for Q47319

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q47319

No associated diseases with Q47319

3 regional properties for Q47319

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 4 - 236 IPR003439
domain AAA+ ATPase domain 33 - 214 IPR003593
conserved_site ABC transporter-like, conserved site 136 - 150 IPR017871

Functions

Description
EC Number 2.5.1.25 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
tRNA-uridine aminocarboxypropyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8NBA8 DTWD2 tRNA-uridine aminocarboxypropyltransferase 2 Homo sapiens (Human) PR
10 20 30 40 50 60
MTENAVLQLR AERIARATRP FLARGNRVRR CQRCLLPEKL CLCSTITPAQ AKSRFCLLMF
70 80 90 100 110 120
DTEPMKPSNT GRLIADILPD TVAFQWSRTE PSQDLLELVQ NPDYQPMVVF PASYADEQRE
130 140 150 160 170 180
VIFTPPAGKP PLFIMLDGTW PEARKMFRKS PYLDNLPVIS VDLSRLSAYR LREAQAEGQY
190 200 210 220 230
CTAEVAIALL DMAGDTGAAA GLGEHFTRFK TRYLAGKTQH LGSITAEQLE SV