Q46DV8

PR
Gene name
kptA
Protein name
Probable RNA 2'-phosphotransferase
Names
Species
Methanosarcina barkeri (strain Fusaro / DSM 804)
KEGG Pathway
mba:Mbar_A0962
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q46DV8

Entry ID Method Resolution Chain Position Source
AF-Q46DV8-F1 Predicted AlphaFoldDB

No variants for Q46DV8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q46DV8

No associated diseases with Q46DV8

5 regional properties for Q46DV8

Type Name Position InterPro Accession
domain Aminoacyl-tRNA synthetase, class II (D/K/N) 162 - 501 IPR004364
domain OB-fold nucleic acid binding domain, AA-tRNA synthetase-type 68 - 146 IPR004365
domain Aminoacyl-tRNA synthetase, class II 184 - 503 IPR006195
domain Lysyl-tRNA synthetase, class II, C-terminal 177 - 503 IPR018149
domain Lysine-tRNA ligase, class II, N-terminal 67 - 174 IPR044136

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
NAD+ ADP-ribosyltransferase activity Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
transferase activity, transferring phosphorus-containing groups Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

1 GO annotations of biological process

Name Definition
tRNA splicing, via endonucleolytic cleavage and ligation Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIRKCTEHGY FRGGSCLQCK RPGRYLLDDN KEEKLGRFVS GTLRHFPESA GVTMDRFGWV
70 80 90 100 110 120
NINDFCDVMR KRYSWMRKEY LYALVESDEK GRYEIRNSRI RARYGHSVNI DLDYRESDSP
130 140 150 160 170 180
YLYYGASPEE VDVLLENGIF PIKQRYVHLS TSYEKAVEVA LIHTENPVIL QIDAFKAQED
190 200
GISLKLATDD IVLAERIPPE YLFVVEE