Q465J4

PR
Gene name
pdxT
Protein name
Pyridoxal 5'-phosphate synthase subunit PdxT
Names
Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit
Species
Methanosarcina barkeri (strain Fusaro / DSM 804)
KEGG Pathway
mba:Mbar_A3580
EC number
3.5.1.2: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

64-155 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q465J4

Entry ID Method Resolution Chain Position Source
AF-Q465J4-F1 Predicted AlphaFoldDB

No variants for Q465J4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q465J4

No associated diseases with Q465J4

1 regional properties for Q465J4

Type Name Position InterPro Accession
conserved_site PdxT/SNO family, conserved site 46 - 56 IPR021196

Functions

Description
EC Number 3.5.1.2 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
glutaminase activity Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.

2 GO annotations of biological process

Name Definition
glutamine catabolic process The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid.
pyridoxal phosphate biosynthetic process The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKIGVIAIQG AVSEHIDALR RALKERGMSA EVVAVKHKGV IPECGGIVIP GGESTTLCRL
70 80 90 100 110 120
LAREGIAEEI KDASARGVPI LGTCAGLIVL SKEGDEQVEK TSQELLGIMD TKVNRNAFGR
130 140 150 160 170 180
QRDSFEAELE VEILDSPFTG VFIRAPGIVS CGPEVRVLSR LDDLIIAAEQ GNVLALAFHP
190
ELTEDLRIHQ YFLDKIFKNA