Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q45263

Entry ID Method Resolution Chain Position Source
AF-Q45263-F1 Predicted AlphaFoldDB

No variants for Q45263

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q45263

No associated diseases with Q45263

5 regional properties for Q45263

Type Name Position InterPro Accession
domain Protein kinase domain 517 - 790 IPR000719
domain Adenylyl cyclase class-3/4/guanylyl cyclase 829 - 1041 IPR001054
domain Serine-threonine/tyrosine-protein kinase, catalytic domain 548 - 787 IPR001245
domain Receptor, ligand binding region 47 - 402 IPR001828
conserved_site Adenylyl cyclase class-4/guanylyl cyclase, conserved site 972 - 995 IPR018297

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFKGLDLNL LVALDALITE RNLSSAARKI NLSQPAMSAA VARLRKHFRD ELFGMRGREL
70 80 90 100 110 120
VLSSRAEGLA APVREALMHI ELSIMARHPF DPARLNRRFR IVLSDFVTVV LFRNVVARVT
130 140 150 160 170 180
REAPAVSFEL AAPTDEHELL LRRGEVDFVI RPDFFMSSTH PRAALFEERL VCVGCCTNRE
190 200 210 220 230 240
LQPRLTFDRY MSMGHVAVKH GGAPRTPVEH SFLTDLGPTR RIDILVQSFS MIPPLIVGTN
250 260 270 280 290 300
RIGTMPLGLV RHFQRTMPLR IVELPHPFPA FTEAVQWPSL HNSDPGSLWM RDILFQEATR
310 320
MATTQELRVT SSPEDAEPPG HFVRSVSPLP