Q44093

PR
Gene name
aroA
Protein name
Phospho-2-dehydro-3-deoxyheptonate aldolase
Names
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase
Species
Amycolatopsis methanolica
KEGG Pathway
EC number
2.5.1.54: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-61 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q44093

Entry ID Method Resolution Chain Position Source
AF-Q44093-F1 Predicted AlphaFoldDB

No variants for Q44093

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q44093

No associated diseases with Q44093

1 regional properties for Q44093

Type Name Position InterPro Accession
domain DAHP synthetase I/KDSA 72 - 203 IPR006218

Functions

Description
EC Number 2.5.1.54 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
3-deoxy-7-phosphoheptulonate synthase activity Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.

3 GO annotations of biological process

Name Definition
aromatic amino acid family biosynthetic process The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
chorismate biosynthetic process The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIDRLVRDSR GPVTERNPPH MSLSAGPAEI SEGLDNQRTL GVSPLISPAL LRQELPVDAA
70 80 90 100 110 120
IAKTVAHGRS SAVDILHGDD DRLIVVVGPC SVHDPAAALD YAHRLAEHAA GVRDELHVIM
130 140 150 160 170 180
RVYFEKPRTT LGWKGLINDP DLDGSYAVNK GLRMARKLLL DISALGLPVG CEFLDPITPQ
190 200
FIADTVSWGS IGARTAASQV HRQ