Q43469

PR
Gene name
sld1
Protein name
Delta(8)-fatty-acid desaturase
Names
Delta(8)-sphingolipid desaturase, Sphingolipid 8-(E/Z)-desaturase
Species
Helianthus annuus (Common sunflower)
KEGG Pathway
EC number
1.14.19.29: With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

66-139 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q43469

Entry ID Method Resolution Chain Position Source
AF-Q43469-F1 Predicted AlphaFoldDB

No variants for Q43469

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q43469

No associated diseases with Q43469

2 regional properties for Q43469

Type Name Position InterPro Accession
domain Cytochrome b5-like heme/steroid binding domain 16 - 100 IPR001199
domain Fatty acid desaturase domain 147 - 417 IPR005804

Functions

Description
EC Number 1.14.19.29 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
sphingolipid delta-8 desaturase activity Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).

1 GO annotations of biological process

Name Definition
sphingolipid metabolic process The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVSPSIEVLN SIADGKKYIT SKELKKHNNP NDLWISILGK VYNVTEWAKE HPGGDAPLIN
70 80 90 100 110 120
LAGQDVTDAF IAFHPGTAWK HLDKLFTGYH LKDYQVSDIS RDYRKLASEF AKAGMFEKKG
130 140 150 160 170 180
HGVIYSLCFV SLLLSACVYG VLYSGSFWIH MLSGAILGLA WMQIAYLGHD AGHYQMMATR
190 200 210 220 230 240
GWNKFAGIFI GNCITGISIA WWKWTHNAHH IACNSLDYDP DLQHLPMLAV SSKLFNSITS
250 260 270 280 290 300
VFYGRQLTFD PLARFFVSYQ HYLYYPIMCV ARVNLYLQTI LLLISKRKIP DRGLNILGTL
310 320 330 340 350 360
IFWTWFPLLV SRLPNWPERV AFVLVSFCVT GIQHIQFTLN HFSGDVYVGP PKGDNWFEKQ
370 380 390 400 410 420
TRGTIDIACS SWMDWFFGGL QFQLEHHLFP RLPRCHLRSI SPICRELCKK YNLPYVSLSF
430 440 450
YDANVTTLKT LRTAALQARD LTNPAPQNLA WEAFNTHG