Q43111

SS
Gene name
MPE3
Protein name
Pectinesterase 3
Names
PE 3, Pectin methylesterase 3
Species
Phaseolus vulgaris (Kidney bean) (French bean)
KEGG Pathway
EC number
3.1.1.11: Carboxylic ester hydrolases
Protein Class

Descriptions

(Annotation from UniProt)
The PMEI region may act as an autoinhibitory domain and prevent untimely PME activity during transport.

Autoinhibitory domains (AIDs)

75-228 (PMEI region) SS

Target domain

273-566 (Pectinesterase domain)

Relief mechanism

Assay

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q43111

Entry ID Method Resolution Chain Position Source
AF-Q43111-F1 Predicted AlphaFoldDB

No variants for Q43111

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q43111

No associated diseases with Q43111

4 regional properties for Q43111

Type Name Position InterPro Accession
domain Pectinesterase, catalytic 273 - 566 IPR000070
domain Pectinesterase inhibitor domain 68 - 232 IPR006501
active_site Pectinesterase, Tyr active site 298 - 317 IPR018040
active_site Pectinesterase, Asp active site 417 - 426 IPR033131

Functions

Description
EC Number 3.1.1.11 Carboxylic ester hydrolases
Subcellular Localization
  • Secreted, cell wall
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

3 GO annotations of molecular function

Name Definition
aspartyl esterase activity Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.
enzyme inhibitor activity Binds to and stops, prevents or reduces the activity of an enzyme.
pectinesterase activity Catalysis of the reaction: pectin + n H2O = n methanol + pectate.

2 GO annotations of biological process

Name Definition
cell wall modification The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.
pectin catabolic process The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDTIKSFKGY GKVNELEQQA YEKKTRKRLI IIAVSSIVLI AVIIAAVAGV VIHNRNSESS
70 80 90 100 110 120
PSSDSVPQTE LSPAASLKAV CDTTRYPSSC FSSISSLPES NTTDPELLFK LSLRVAIDEL
130 140 150 160 170 180
SSFPSKLRAN AEQDARLQKA IDVCSSVFGD ALDRLNDSIS ALGTVAGRIA SSASVSNVET
190 200 210 220 230 240
WLSAALTDQD TCLDAVGELN STAARGALQE IETAMRNSTE FASNSLAIVT KILGLLSRFE
250 260 270 280 290 300
TPIHHRRLLG FPEWLGAAER RLLEEKNNDS TPDAVVAKDG SGQFKTIGEA LKLVKKKSEE
310 320 330 340 350 360
RFSVYVKEGR YVENIDLDKN TWNVMIYGDG KDKTFVVGSR NFMDGTPTFE TATFAVKGKG
370 380 390 400 410 420
FIAKDIGFVN NAGASKHQAV ALRSGSDRSV FFRCSFDGFQ DTLYAHSNRQ FYRDCDITGT
430 440 450 460 470 480
IDFIFGNAAV VFQSCKIMPR QPLPNQFNTI TAQGKKDPNQ NTGIIIQKST ITPFGNNLTA
490 500 510 520 530 540
PTYLGRPWKD FSTTVIMQSD IGALLNPVGW MSWVPNVEPP TTIFYAEYQN SGPGADVSQR
550 560 570 580
VKWAGYKPTI TDRNAEEFTV QSFIQGPEWL PNAAVQFDST L