Q3Z9C1

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) (Dehalococcoides ethenogenes (strain 195))
KEGG Pathway
det:DET0434
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

870-952 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3Z9C1

Entry ID Method Resolution Chain Position Source
AF-Q3Z9C1-F1 Predicted AlphaFoldDB

No variants for Q3Z9C1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3Z9C1

No associated diseases with Q3Z9C1

9 regional properties for Q3Z9C1

Type Name Position InterPro Accession
domain Helicase, C-terminal 497 - 683 IPR001650
conserved_site SEC-C motif 934 - 952 IPR004027
domain SecA DEAD-like, N-terminal 4 - 465 IPR011115
domain SecA Wing/Scaffold 670 - 879 IPR011116
domain SecA, preprotein cross-linking domain 303 - 421 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 137 - 322 IPR014001
domain SecA motor DEAD 1 - 672 IPR014018
conserved_site SecA conserved site 563 - 578 IPR020937
domain SecA, C-terminal helicase domain 483 - 641 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFKFFSGFGD SNEKEIRALE PLVDKINQLE SSFSALSDEA LKAKTAEFKE RLKETFETTA
70 80 90 100 110 120
SAILKDIAGT TAELEEAQKT ADNSKQSRLK AKLESLNKDL SVKENAALNA ILPEAFAAVR
130 140 150 160 170 180
EASRRTIGLR HYDVQLIGGM VLHHGKIAEM RTGEGKTLVA TLPLYLNSLL GKGVHLVTVN
190 200 210 220 230 240
DYLARRDAYW MGPVYHALGV SVSSIYPMQT PTEELPSRLF DPTYTSETPN DPWMHFRPIS
250 260 270 280 290 300
RQEAYKADIT YGTSTEFGFD YLRDNLRPDL AQCVQREMNY AIVDEIDNLL IDEARTPLII
310 320 330 340 350 360
SAPDTEAGKL YEVFARLAPR LAAGKDYEIN EKDRNAELTE DGWANVEKLL SREGVMKGSS
370 380 390 400 410 420
LYDPQNAPLI RHLRNALSAK EFYKKDHQYV VKENEVIIID EFTGRMMLGR RYSEGLHQAI
430 440 450 460 470 480
EAKEHVKIQQ ESKTYATVTI QNLFRMYRKL CGMTGTAATE AEEFSKIYKL EVVIIPTNKP
490 500 510 520 530 540
AIREDYGDQI YKDQSAKFKA VVNEINEMRN LGRPVLVGTV SIENSEMLSN MLKRQGIEHK
550 560 570 580 590 600
VLNAKQHEKE AQVVAEAGKP GAVTVATNMA GRGVDILLGG KEPPKDDDKA YSQWQVHHQQ
610 620 630 640 650 660
VLEAGGLHVI GTERHESRRI DNQLRGRSGR QGDPGSSRFY VALDDDIMRR FGSERIQGIM
670 680 690 700 710 720
EWAGMDENTP IENGLVSRTL ENAQKRVEGY HFDVRKHLVE YDDVVNKHRE VIYAERRKIL
730 740 750 760 770 780
LGADLKSNIL DMIREEIMTQ TAEHTQGYDS SEWNLEGLVT HIGGIFALPA EINAEALAKL
790 800 810 820 830 840
SQEEITELLT RTAEELYQKK EAEIGAGSMR LLERIIMLHT LDSLWVEHLT IMENLRREIG
850 860 870 880 890 900
LQAFAQRDPL IAYKNEGHVR FQELLETIKH DVVHNIYRVN IQIQHQTESA TAKAASRPVQ
910 920 930 940 950
QQKPLPAAPA AAIPGVSAKA ATQPAAPAAK EVGRNDPCPC GSGKKYKKCC GK