Q3Z5W2
Gene name |
kefC |
Protein name |
Glutathione-regulated potassium-efflux system protein KefC |
Names |
K(+)/H(+) antiporter |
Species |
Shigella sonnei (strain Ss046) |
KEGG Pathway |
ssn:SSON_0055 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3Z5W2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3Z5W2-F1 | Predicted | AlphaFoldDB |
No variants for Q3Z5W2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3Z5W2 | |||||
No associated diseases with Q3Z5W2
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| enzyme binding | Binding to an enzyme, a protein with catalytic activity. |
| glutathione-regulated potassium exporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state. |
| solute:proton antiporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out). |
| toxic substance binding | Binding to a toxic substance, a poisonous substance that causes damage to biological systems. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| response to methylglyoxal | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSHTLIQAL | IYLGSAALIV | PIAVRLGLGS | VLGYLIAGCI | IGPWGLRLVT | DAESILHFAE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IGVVLMLFII | GLELDPQRLW | KLRAAVFGGG | ALQMVICGGL | LGLFCMLLGL | HWQVAELIGM |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TLALSSTAIA | MQAMNERNLM | VTQMGRSAFA | VLLFQDIAAI | PLVAMIPLLA | TSSASTTMGA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FALSALKVAG | ALVLVVLLGR | YVTRPALRFV | ARSGLREVFS | AVALFLVFGF | GLLLEEVGLS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MAMGAFLAGV | LLASSEYRHA | LESDIEPFKG | LLLGLFFIGV | GMSIDFGTLL | ENPLRIVILL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LGFLIIKIAM | LWLIARPLQV | PNKQRRWFAV | LLGQGSEFAF | VVFGTAQMAN | VLEPEWAKSL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TLAVALSMAA | TPILLVILNR | LEQSSTEEAR | EADEIDEEQP | RVIIAGFGRF | GQITGRLLLS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SGVKMVVLDH | DPDHIETLRK | FGMKVFYGDA | TRMDLLESAG | AAKAEVLINA | IDDPQTNLQL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TEMVKEHFPH | LQIIARARDV | DHYIRLRQAG | VEKPERETFE | GALKTGRLAL | ESLGLGPYEA |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RERADVFRRF | NIQMVEEMAM | VENDTKARAA | VYKRTSAMLS | EIITEDREHL | SLIQRHGWQG |
| 610 | |||||
| TEEGKHTGNM | ADEPETKPSS |