Q3UN16
Gene name |
Gpr162 |
Protein name |
Probable G-protein coupled receptor 162 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:14788 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3UN16
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3UN16-F1 | Predicted | AlphaFoldDB |
18 variants for Q3UN16
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388836792 | 4 | G>E | No | EVA | |
| rs3388841894 | 41 | K>E | No | EVA | |
| rs3388844749 | 158 | N>I | No | EVA | |
| rs3396915910 | 178 | G>D | No | EVA | |
| rs3388854299 | 205 | T>A | No | EVA | |
| rs3388823612 | 209 | R>Q | No | EVA | |
| rs262110236 | 225 | T>A | No | EVA | |
| rs3388855170 | 271 | N>I | No | EVA | |
| rs3388858326 | 302 | P>Q | No | EVA | |
| rs3388861918 | 328 | E>* | No | EVA | |
| rs3388850503 | 334 | V>E | No | EVA | |
| rs3388863546 | 415 | D>N | No | EVA | |
| rs3388866800 | 415 | D>V | No | EVA | |
| rs3397169161 | 494 | P>A | No | EVA | |
| rs3397309540 | 494 | P>R | No | EVA | |
| rs3397306925 | 495 | P>L | No | EVA | |
| rs3388854321 | 517 | P>Q | No | EVA | |
| rs3388850435 | 565 | S>I | No | EVA |
No associated diseases with Q3UN16
1 regional properties for Q3UN16
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 30 - 280 | IPR017452 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| G protein-coupled receptor activity | Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q16538 | GPR162 | Probable G-protein coupled receptor 162 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARGGLGAEE | ASLRSNALSW | LACGLLALLA | NAWIILSISA | KQQKHKPLEL | LLCFLAGTHI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LMAAVPLTTF | AVVQLRRQAS | SDYDWNESIC | KVFVSTYYTL | ALATCFTVAS | LSYHRMWMVR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WPVNYRLSNA | KKQALHAVMG | IWMVSFILST | LPSIGWHNNG | ERYYARGCQF | IVSKIGLGFG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VCFSLLLLGG | IVMGLVCVAI | TFYQTLWARP | RRARQARRAG | GSVGTKAGGL | GGLGTRPAFE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VPAIVVEDTR | GKRRSSLDGS | ESAKTSLQVT | NLVSAIVFLY | DSLTGVPILV | VSFFSLKSDS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| APPWMVLAVL | WCSMAQTLLL | PSFIWSCERY | RADVRTVWEQ | CVAIMSEDDG | DDDGTCDDYT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DGRVCKIRFD | ANGATGSGSR | DPTQVKLLPG | RHMLFPPLER | VHYLQVPLSR | RLSHDETNIF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| STPRAPGSFL | HKWSSSDDIR | ILPAQSRALG | GPPEYLGQRH | RLEDEEDEEE | AEGGGLASLR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QFLESGVLGS | GGGPPRGPGF | FREEITTFID | ETPLPSPTAS | PGPSPRRPRP | LGFSPRRLSL |
| 550 | 560 | 570 | 580 | ||
| GSPDSRAVGL | PLGLSAGRRC | SLTGSEGSSR | AWGRPWGPGN | PIFPQLTL |