Q3UHD2

PR
Gene name
Gfod1
Protein name
Glucose-fructose oxidoreductase domain-containing protein 1
Names
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:328232
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

244-318 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3UHD2

Entry ID Method Resolution Chain Position Source
AF-Q3UHD2-F1 Predicted AlphaFoldDB

21 variants for Q3UHD2

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389296048 91 I>N No EVA
rs3389253327 97 T>M No EVA
rs3389280259 137 E>D No EVA
rs3389280218 152 S>VSDG* No EVA
rs3389281867 155 L>V No EVA
rs3389288886 156 L>Q No EVA
rs3389277314 156 L>V No EVA
rs3389283153 168 M>L No EVA
rs3403669748 175 S>A No EVA
rs3404088248 175 S>C No EVA
rs3389281227 201 T>I No EVA
rs3389288834 202 F>L No EVA
rs3404020344 216 T>I No EVA
rs3389280263 260 A>* No EVA
rs3389280224 260 A>E No EVA
rs3389280236 294 A>T No EVA
rs3389273020 305 G>D No EVA
rs3389296086 317 F>V No EVA
rs3389280300 321 D>Y No EVA
rs3389272973 354 S>N No EVA
rs3389296142 388 L>R No EVA

No associated diseases with Q3UHD2

2 regional properties for Q3UHD2

Type Name Position InterPro Accession
domain Gfo/Idh/MocA-like oxidoreductase, N-terminal 5 - 110 IPR000683
domain Gfo/Idh/MocA-like oxidoreductase, C-terminal 132 - 359 IPR004104

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6P4M5 gfod1 Glucose-fructose oxidoreductase domain-containing protein 1 Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MLPGVGVFGT SLTARVIIPL LKDEGFAVKA LWGRTQEEAE ELAKEMSVPF YTSRIDEVLL
70 80 90 100 110 120
HQDVDLVCIN LPPPLTRQIA VKTLGIGKNV ICDRTATPLD AFRMMSAAHY YPKLMSIMGN
130 140 150 160 170 180
VLRFLPAFVR MKQLIEEGYV GELLVCEVQV HSGSLLGKKY NWSCDDLMGG GGLHSVGTYI
190 200 210 220 230 240
IDLLTFLTGQ KAVKVHGLLK TFVKQTDHIK GIRQITSDDF CTFQMVLEGG VCCTVTLNFN
250 260 270 280 290 300
VPGEFKQDVT VVGSAGRLLA VGTDLYGQRN SAPEQELLLQ DTTSVSNSLL PEKAFSDIPS
310 320 330 340 350 360
PYLRGTMKMM QAVRQAFQDQ DDRRTWDGRP LTMAATFDDC LYALCVVDTI KRSSQTGEWQ
370 380
NIAIMTEEPE LSPAYLISEA MRRSRMSLYC