Q3TAA7
PR
Gene name |
Stk11ip (Lip1, Lkb1ip) |
Protein name |
Serine/threonine-protein kinase 11-interacting protein |
Names |
LKB1-interacting protein 1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:71728 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3TAA7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3TAA7-F1 | Predicted | AlphaFoldDB |
80 variants for Q3TAA7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388481045 | 4 | A>S | No | EVA | |
| rs3388480296 | 13 | L>Q | No | EVA | |
| rs3388481949 | 24 | V>L | No | EVA | |
| rs3388481308 | 28 | C>Y | No | EVA | |
| rs3388481125 | 64 | S>F | No | EVA | |
| rs3388480428 | 66 | P>S | No | EVA | |
| rs3388481016 | 81 | V>E | No | EVA | |
| rs3388480723 | 88 | L>V | No | EVA | |
| rs3388479607 | 90 | L>M | No | EVA | |
| rs3388479544 | 118 | V>G | No | EVA | |
| rs3388481301 | 130 | Y>C | No | EVA | |
| rs3388480940 | 131 | S>P | No | EVA | |
| rs3388481158 | 138 | C>R | No | EVA | |
| rs3388479782 | 139 | N>S | No | EVA | |
| rs3388479832 | 140 | R>S | No | EVA | |
| rs3388480193 | 141 | S>T | No | EVA | |
| rs3388479778 | 148 | L>F | No | EVA | |
| rs3388480431 | 158 | S>Y | No | EVA | |
| rs253227269 | 176 | R>S | No | EVA | |
| rs3388480252 | 179 | D>H | No | EVA | |
| rs3388481027 | 182 | L>P | No | EVA | |
| rs3388483330 | 224 | V>M | No | EVA | |
| rs3390049879 | 277 | L>Q | No | EVA | |
| rs3390204987 | 278 | L>P | No | EVA | |
| rs231926394 | 279 | A>G | No | EVA | |
| rs3388483332 | 281 | L>F | No | EVA | |
| rs3388479794 | 282 | R>H | No | EVA | |
| rs3388483191 | 285 | Y>C | No | EVA | |
| rs3390214171 | 297 | H>R | No | EVA | |
| rs37965205 | 322 | V>I | No | EVA | |
| rs3388481313 | 331 | T>S | No | EVA | |
| rs32223536 | 340 | V>M | No | EVA | |
| rs3388481143 | 349 | G>E | No | EVA | |
| rs37684445 | 364 | L>F | No | EVA | |
| rs3388481980 | 398 | E>* | No | EVA | |
| rs3388482476 | 446 | L>V | No | EVA | |
| rs3388479859 | 470 | P>L | No | EVA | |
| rs260416709 | 474 | E>G | No | EVA | |
| rs32608998 | 482 | E>K | No | EVA | |
| rs3388481033 | 486 | E>* | No | EVA | |
| rs3388481161 | 548 | F>L | No | EVA | |
| rs3390204942 | 565 | R>Q | No | EVA | |
| rs3390182514 | 568 | E>* | No | EVA | |
| rs3388483263 | 576 | V>M | No | EVA | |
| rs250907735 | 586 | T>S | No | EVA | |
| rs3388483264 | 602 | P>Q | No | EVA | |
| rs3388479824 | 604 | L>I | No | EVA | |
| rs251574136 | 657 | G>R | No | EVA | |
| rs3388481402 | 658 | A>G | No | EVA | |
| rs3388479545 | 688 | F>S | No | EVA | |
| rs3388480736 | 690 | N>Y | No | EVA | |
| rs3388479857 | 710 | V>M | No | EVA | |
| rs36460013 | 719 | Q>R | No | EVA | |
| rs223440716 | 734 | D>N | No | EVA | |
| rs238432795 | 754 | D>G | No | EVA | |
| rs255522776 | 755 | R>H | No | EVA | |
| rs3388481382 | 771 | S>P | No | EVA | |
| rs3388481004 | 803 | A>S | No | EVA | |
| rs3388481464 | 808 | E>V | No | EVA | |
| rs3388480263 | 831 | G>R | No | EVA | |
| rs3388480410 | 862 | L>P | No | EVA | |
| rs3388481420 | 863 | E>K | No | EVA | |
| rs3388480226 | 871 | C>R | No | EVA | |
| rs260972506 | 878 | A>D | No | EVA | |
| rs3390206109 | 880 | Q>H | No | EVA | |
| rs239231514 | 897 | R>C | No | EVA | |
| rs3388480753 | 904 | S>T | No | EVA | |
| rs227764637 | 913 | Q>K | No | EVA | |
| rs3388479553 | 960 | D>E | No | EVA | |
| rs3388481049 | 975 | V>M | No | EVA | |
| rs3388483237 | 979 | T>I | No | EVA | |
| rs3388481437 | 990 | P>R | No | EVA | |
| rs3388479550 | 1032 | A>P | No | EVA | |
| rs3388481150 | 1035 | V>L | No | EVA | |
| rs3388479869 | 1047 | W>* | No | EVA | |
| rs3388483230 | 1052 | W>C | No | EVA | |
| rs3388480432 | 1060 | L>F | No | EVA | |
| rs3388482496 | 1063 | V>E | No | EVA | |
| rs3388480399 | 1067 | A>T | No | EVA | |
| rs3388480204 | 1072 | R>* | No | EVA |
No associated diseases with Q3TAA7
1 regional properties for Q3TAA7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | LKB1 serine/threonine kinase interacting protein 1, N-terminal | 7 - 94 | IPR031782 |
Functions
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| intracellular membrane-bounded organelle | Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein kinase binding | Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein localization | Any process in which a protein is transported to, or maintained in, a specific location. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8N1F8 | STK11IP | Serine/threonine-protein kinase 11-interacting protein | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTAPRDSVV | WKLAGLLRES | GDAVLSGCST | LSLLTATLQQ | LNRVFELYLG | PWGPGQTGFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALPSHPADSP | VILQLQFLFD | VLQKTLSLKL | VHIPGVGLPG | PIKIFPFKSL | RQLELRGVPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HSLCGLRGIY | SQLESLVCNR | SIQALEELLS | ACGGDLCSAL | PWLALLSADF | SYNALRSLDS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SLRLLSALRF | LNLSHNHLQD | CKGFLMDLCE | LYHLDISYNH | LRLVPRVGPS | GAALGTLILR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ANELRSLQGL | EQLKNLRHLD | VAYNLLEGHT | ELAPLWLLAE | LRKLYLEGNP | LWFHPAHRAA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TAQYLSPRAR | DAAHGFLLDG | KVLSLKDLQQ | TSDSSGLGPV | IQPLSWPVGS | TTETSGGPEL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SDSLSSGGIV | AQAPLRKVKS | RVRVRRASIS | EPSDTDPELR | TLDPSPAGWF | VQQHRELELL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ASFRERFGCD | WLQYRSHLET | MGSSPLSTTK | TPALSTPPLD | VQNLETVCSP | PAIEDDTKES |
| 490 | 500 | 510 | 520 | 530 | 540 |
| PEKVSEEGRV | EPEPQEEERE | EQDKEEGSRE | DLEEEEEQEQ | KAVEAELCRP | MLVCPLQGLG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| GVQGKECFLR | VTSAHLFEVE | LQAARTLERL | ELQSLVAAEL | ESETETQGEP | VSEGSGPFPG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| APVLVLRFSY | ICPDRQLRRY | AVLEPEAREA | VQELLAVLTP | FTSVKEQQPG | ANKDPQGARF |
| 670 | 680 | 690 | 700 | 710 | 720 |
| QCLRCSCEFK | PEESRLGLES | DEGWKPLFQN | TESPVVCPNC | GSDHVVLLAV | SGEVPNREQN |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QEEQSADSAC | DLADHGGCPS | RPDGIPPQTS | ISHDRSSWSL | SPSPGCSGFR | SVDHRLRLFL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| DVEVFSDSEE | EFQCCIKVPV | VLAGHTEEFP | CLVVVSNHML | YLLKVLGAIC | GPPASWLQPT |
| 850 | 860 | 870 | 880 | 890 | 900 |
| LAIALQDLSG | MELGLAGQSL | RLEWAAGTGS | CVLLPRDARQ | CRAFLEELTG | VLQSLPRTQR |
| 910 | 920 | 930 | 940 | 950 | 960 |
| NCISATEEEV | TPQHRLWPLL | GKDPSAEVPQ | FFYLRAFLAE | GSSTCPVSLL | LTLSTLYLLD |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| EDPGGSHAES | PLPVVSDETS | EQPASLGPGP | SLQVREQQPL | SCLSSVQLYR | TSPLDLRLIF |
| 1030 | 1040 | 1050 | 1060 | 1070 | |
| YDEVSRLESF | WALHVVCGEQ | LTALLAWIRE | PWEELFSIGL | RTVTQEALDL | DR |