Q3T131

PR
Gene name
COQ3
Protein name
Ubiquinone biosynthesis O-methyltransferase, mitochondrial
Names
3-demethylubiquinol 3-O-methyltransferase, Polyprenyldihydroxybenzoate methyltransferase
Species
Bos taurus (Bovine)
KEGG Pathway
bta:540298
EC number
2.1.1.64: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3T131

Entry ID Method Resolution Chain Position Source
AF-Q3T131-F1 Predicted AlphaFoldDB

No variants for Q3T131

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3T131

No associated diseases with Q3T131

No regional properties for Q3T131

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q3T131

Functions

Description
EC Number 2.1.1.64 Methyltransferases
Subcellular Localization
  • Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extrinsic component of mitochondrial inner membrane The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.

3 GO annotations of molecular function

Name Definition
2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
3-demethylubiquinone-9 3-O-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.
hexaprenyldihydroxybenzoate methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.

2 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
ubiquinone biosynthetic process The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWGGSKLSSS GSRFLGALRS GFQSTQVDSS RLTTSAVYPK NQLSWILQIK PWVFNENRIM
70 80 90 100 110 120
WFKSYSITFA CLNWMKSYRL PWTRPYSTSR TTVDKNEMKT FLALAHRWWD EQGVYAPLHS
130 140 150 160 170 180
MNDLRVPFIR DNLLRTVATH QPGKPLSGMK ILDVGCGGGL LTEPLGRLGA SVIGIDPVDE
190 200 210 220 230 240
NIKTAQHHKS FDPVLDKRIE YRTCSLEEIV KDTVETFDAV VASEVVEHVI DLETFIQCCF
250 260 270 280 290 300
QVLKPDGSLF ITTINKTQLS YALGIVFSEQ IAGIVPKGTH TWEKFVSPEK LESILESNGL
310 320 330 340 350 360
SVQTVVGMLY NPFSGYWHWS ENTSLNYAAH ALKSSLQEQP APAEFALKGE AEELQAEAST
NSGVQEDLKK