Q3SUS4
Gene name |
Nwi_0701 |
Protein name |
PKHD-type hydroxylase Nwi_0701 |
Names |
|
Species |
Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) |
KEGG Pathway |
nwi:Nwi_0701 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3SUS4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3SUS4-F1 | Predicted | AlphaFoldDB |
No variants for Q3SUS4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q3SUS4 | |||||
No associated diseases with Q3SUS4
4 regional properties for Q3SUS4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Oxoglutarate/iron-dependent dioxygenase | 78 - 178 | IPR005123 |
| domain | Prolyl 4-hydroxylase, alpha subunit | 1 - 177 | IPR006620 |
| domain | PKHD-type hydroxylase C-terminal domain | 185 - 225 | IPR041097 |
| domain | Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain | 83 - 176 | IPR044862 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2-oxoglutarate-dependent dioxygenase activity | Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor. |
| iron ion binding | Binding to an iron (Fe) ion. |
| L-ascorbic acid binding | Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIQVISDVLT | PDELKRFREL | LGQAQWQDGR | ATAGHVAVRA | KANEQLSHED | SLGQQLSEFL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LERLGKISHF | IAAALPLKVL | PPRFNRYTGG | GSYGDHIDNA | IFSVPGAGVR | IRGDLSATLF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSEPGDYDGG | ELIIQGEFAR | HQFKLPAGQM | ILYPASTFHQ | VTPVTRGARL | AAFFWTQSLV |
| 190 | 200 | 210 | 220 | ||
| REHSRRALLF | ELDNTIQALA | QDNPEQPAVA | RLTGLYHNLL | REWSET |